| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AF_0058 | AF_0239 | AF_0058 | AF_0239 | Conserved hypothetical protein; Similar to GB:L77117 PID:1592059 percent identity: 36.08; identified by sequence similarity; putative; Belongs to the UPF0113 family. | Xanthine-guanine phosphoribosyltransferase (gptA-1); Similar to GB:L42023 SP:P43859 PID:1005561 PID:1005597 PID:1220758 percent identity: 25.71; identified by sequence similarity; putative. | 0.497 |
| AF_0058 | rpoL | AF_0058 | AF_0207 | Conserved hypothetical protein; Similar to GB:L77117 PID:1592059 percent identity: 36.08; identified by sequence similarity; putative; Belongs to the UPF0113 family. | DNA-directed RNA polymerase, subunit L (rpoL); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. | 0.892 |
| AF_0058 | rtcA | AF_0058 | AF_1435 | Conserved hypothetical protein; Similar to GB:L77117 PID:1592059 percent identity: 36.08; identified by sequence similarity; putative; Belongs to the UPF0113 family. | Conserved hypothetical protein; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity). | 0.910 |
| AF_0058 | truB | AF_0058 | AF_0238 | Conserved hypothetical protein; Similar to GB:L77117 PID:1592059 percent identity: 36.08; identified by sequence similarity; putative; Belongs to the UPF0113 family. | Centromere/microtubule-binding protein (cbf5); Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.686 |
| AF_0239 | AF_0058 | AF_0239 | AF_0058 | Xanthine-guanine phosphoribosyltransferase (gptA-1); Similar to GB:L42023 SP:P43859 PID:1005561 PID:1005597 PID:1220758 percent identity: 25.71; identified by sequence similarity; putative. | Conserved hypothetical protein; Similar to GB:L77117 PID:1592059 percent identity: 36.08; identified by sequence similarity; putative; Belongs to the UPF0113 family. | 0.497 |
| AF_0239 | AF_1788 | AF_0239 | AF_1788 | Xanthine-guanine phosphoribosyltransferase (gptA-1); Similar to GB:L42023 SP:P43859 PID:1005561 PID:1005597 PID:1220758 percent identity: 25.71; identified by sequence similarity; putative. | Methylthioadenosine phosphorylase (mtaP); Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | 0.444 |
| AF_0239 | ade | AF_0239 | AF_0240 | Xanthine-guanine phosphoribosyltransferase (gptA-1); Similar to GB:L42023 SP:P43859 PID:1005561 PID:1005597 PID:1220758 percent identity: 25.71; identified by sequence similarity; putative. | Adenine deaminase (adeC); Similar to GB:L77117 PID:1592101 percent identity: 39.47; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | 0.779 |
| AF_0239 | rpoL | AF_0239 | AF_0207 | Xanthine-guanine phosphoribosyltransferase (gptA-1); Similar to GB:L42023 SP:P43859 PID:1005561 PID:1005597 PID:1220758 percent identity: 25.71; identified by sequence similarity; putative. | DNA-directed RNA polymerase, subunit L (rpoL); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. | 0.460 |
| AF_0239 | rtcA | AF_0239 | AF_1435 | Xanthine-guanine phosphoribosyltransferase (gptA-1); Similar to GB:L42023 SP:P43859 PID:1005561 PID:1005597 PID:1220758 percent identity: 25.71; identified by sequence similarity; putative. | Conserved hypothetical protein; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity). | 0.405 |
| AF_0239 | truB | AF_0239 | AF_0238 | Xanthine-guanine phosphoribosyltransferase (gptA-1); Similar to GB:L42023 SP:P43859 PID:1005561 PID:1005597 PID:1220758 percent identity: 25.71; identified by sequence similarity; putative. | Centromere/microtubule-binding protein (cbf5); Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.564 |
| AF_1788 | AF_0239 | AF_1788 | AF_0239 | Methylthioadenosine phosphorylase (mtaP); Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage. | Xanthine-guanine phosphoribosyltransferase (gptA-1); Similar to GB:L42023 SP:P43859 PID:1005561 PID:1005597 PID:1220758 percent identity: 25.71; identified by sequence similarity; putative. | 0.444 |
| ade | AF_0239 | AF_0240 | AF_0239 | Adenine deaminase (adeC); Similar to GB:L77117 PID:1592101 percent identity: 39.47; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Xanthine-guanine phosphoribosyltransferase (gptA-1); Similar to GB:L42023 SP:P43859 PID:1005561 PID:1005597 PID:1220758 percent identity: 25.71; identified by sequence similarity; putative. | 0.779 |
| ade | truB | AF_0240 | AF_0238 | Adenine deaminase (adeC); Similar to GB:L77117 PID:1592101 percent identity: 39.47; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. | Centromere/microtubule-binding protein (cbf5); Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.549 |
| rpoL | AF_0058 | AF_0207 | AF_0058 | DNA-directed RNA polymerase, subunit L (rpoL); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. | Conserved hypothetical protein; Similar to GB:L77117 PID:1592059 percent identity: 36.08; identified by sequence similarity; putative; Belongs to the UPF0113 family. | 0.892 |
| rpoL | AF_0239 | AF_0207 | AF_0239 | DNA-directed RNA polymerase, subunit L (rpoL); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. | Xanthine-guanine phosphoribosyltransferase (gptA-1); Similar to GB:L42023 SP:P43859 PID:1005561 PID:1005597 PID:1220758 percent identity: 25.71; identified by sequence similarity; putative. | 0.460 |
| rpoL | rtcA | AF_0207 | AF_1435 | DNA-directed RNA polymerase, subunit L (rpoL); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. | Conserved hypothetical protein; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity). | 0.605 |
| rtcA | AF_0058 | AF_1435 | AF_0058 | Conserved hypothetical protein; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity). | Conserved hypothetical protein; Similar to GB:L77117 PID:1592059 percent identity: 36.08; identified by sequence similarity; putative; Belongs to the UPF0113 family. | 0.910 |
| rtcA | AF_0239 | AF_1435 | AF_0239 | Conserved hypothetical protein; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity). | Xanthine-guanine phosphoribosyltransferase (gptA-1); Similar to GB:L42023 SP:P43859 PID:1005561 PID:1005597 PID:1220758 percent identity: 25.71; identified by sequence similarity; putative. | 0.405 |
| rtcA | rpoL | AF_1435 | AF_0207 | Conserved hypothetical protein; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity). | DNA-directed RNA polymerase, subunit L (rpoL); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. | 0.605 |
| rtcA | truB | AF_1435 | AF_0238 | Conserved hypothetical protein; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity). | Centromere/microtubule-binding protein (cbf5); Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.510 |