Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0243Conserved hypothetical protein; Similar to GB:L77117 PID:1590999 percent identity: 45.88; identified by sequence similarity; putative. (529 aa)    
Predicted Functional Partners:
AF_0242
Glucose-1-phosphate thymidylyltransferase (graD-1); Similar to PID:763512 percent identity: 27.69; identified by sequence similarity; putative.
       0.787
mptE
Conserved hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family.
 
     0.632
AF_0241
Conserved hypothetical protein; Similar to GB:L77117 PID:1500478 percent identity: 43.14; identified by sequence similarity; putative.
       0.560
AF_1217
Conserved hypothetical protein; Similar to GB:L77117 SP:Q60332 PID:1498780 percent identity: 39.94; identified by sequence similarity; putative.
 
     0.525
cdc6-1
Cell division control protein 6, putative; Involved in regulation of DNA replication.
       0.507
AF_2029
Conserved hypothetical protein; Similar to GB:L77117 PID:1592223 percent identity: 39.41; identified by sequence similarity; putative.
       0.486
AF_0280
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58074 PID:1591373 percent identity: 46.88; identified by sequence similarity; putative.
       0.468
priL
Conserved hypothetical protein; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
 
    0.462
AF_1966
Conserved hypothetical protein; Similar to GB:L77117 PID:1591643 percent identity: 28.65; identified by sequence similarity; putative.
  
     0.454
atpF
H+-transporting ATP synthase, subunit F (atpF); Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
     0.436
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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