Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AF_0251Predicted coding region AF_0251; Hypothetical protein; identified by GeneMark; putative. (394 aa)    
Predicted Functional Partners:
dtdA
Conserved hypothetical protein; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
  
    0.643
AF_0846
Na+/H+ antiporter (nhe2); Similar to PID:1653577 percent identity: 33.13; identified by sequence similarity; putative.
   
 
 0.576
pyrG
CTP synthase (pyrG); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
       0.530
AF_0964
acyl-CoA dehydrogenase (acd-6); Similar to PID:1055219 SP:P52042 percent identity: 35.77; identified by sequence similarity; putative.
  
  
 0.502
AF_0788
Conserved hypothetical protein; Similar to GB:D26185 SP:P37511 PID:467365 GB:AL009126 percent identity: 25.84; identified by sequence similarity; putative.
  
  
 0.498
pstB
Phosphate ABC transporter, ATP-binding protein (pstB); Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
   
 0.494
AF_1287
acetyl-CoA synthetase (acs-6); Similar to GB:L17309 SP:P39062 PID:348053 PID:2293224 GB:AL009126 percent identity: 34.29; identified by sequence similarity; putative.
 
   
 0.484
guaAB
GMP synthase (guaA-1); Catalyzes the synthesis of GMP from XMP.
       0.471
purC
Phosphoribosylaminoimidazolesuccinocarboxamide synthase (purC); Similar to GB:L77117 PID:1592203 percent identity: 34.71; identified by sequence similarity; putative; Belongs to the SAICAR synthetase family. Highly divergent.
 
   
 0.466
AF_0458
Phosphomannomutase (pmm); Similar to GB:L77117 PID:1591745 percent identity: 39.46; identified by sequence similarity; putative; Belongs to the phosphohexose mutase family.
     
 0.462
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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