Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0254NADH oxidase (noxA-1); Similar to GB:L77117 SP:Q58065 PID:1591361 percent identity: 35.14; identified by sequence similarity; putative. (439 aa)    
Predicted Functional Partners:
hmeD
Heterodisulfide reductase, subunit D, putative; Has menaquinol-oxidizing activity. HmeC and HmeD subunits may together mediate electron transfer from menaquinol to an unidentified electron acceptor on the cytoplasmic side of the membrane.
  
 
 0.910
AF_0395
NADH oxidase (noxA-2); Similar to GB:L77117 SP:Q58065 PID:1591361 percent identity: 35.45; identified by sequence similarity; putative.
  
  
 
0.903
AF_0557
Flavoprotein reductase; Similar to GP:1480407 percent identity: 26.19; identified by sequence similarity; putative.
    
  0.903
hmeA
Molybdopterin oxidoreductase, iron-sulfur binding subunit; Has menaquinol-oxidizing activity. HmeA, HmeB and HmeE subunits may together catalyze electron transfer from menaquinol to cytochrome c.
    
  0.901
hmeC
Nitrate reductase, gamma subunit, putative; Has menaquinol-oxidizing activity. HmeC and HmeD subunits may together mediate electron transfer from menaquinol to an unidentified electron acceptor on the cytoplasmic side of the membrane.
    
  0.901
AF_0546
Nitrate reductase, gamma subunit (narI); Similar to GB:Z26255 percent identity: 30.14; identified by sequence similarity; putative.
    
  0.901
hmeB
Molybdopterin oxidoreductase, membrane subunit; Has menaquinol-oxidizing activity. HmeB subunit may function as a menaquinol-oxidizing site. HmeA, HmeB and HmeE subunits may together catalyze electron transfer from menaquinol to cytochrome c.
    
  0.900
hmeE
Predicted coding region AF_0503; Has menaquinol-oxidizing activity. HmeA, HmeB and HmeE subunits may together catalyze electron transfer from menaquinol to cytochrome c.
     
  0.900
AF_0274
Sarcosine oxidase, subunit beta (soxB); Similar to SP:P40875 PID:927589 percent identity: 26.45; identified by sequence similarity; putative.
  
 
 0.721
AF_0272
Conserved hypothetical protein; Similar to GP:1934608 percent identity: 31.30; identified by sequence similarity; putative.
  
    0.477
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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