node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AF_0358 | AF_2350 | AF_0358 | AF_2350 | DNA repair protein RAD25; Similar to GB:M31899 SP:P19447 PID:182179 percent identity: 32.49; identified by sequence similarity; putative. | ATP-dependent RNA helicase HepA, putative; Similar to SP:P54509 PID:1303889 GB:AL009126 percent identity: 31.49; identified by sequence similarity; putative. | 0.964 |
AF_0358 | fen | AF_0358 | AF_0264 | DNA repair protein RAD25; Similar to GB:M31899 SP:P19447 PID:182179 percent identity: 32.49; identified by sequence similarity; putative. | DNA repair protein RAD2 (rad2); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) [...] | 0.982 |
AF_0358 | lig | AF_0358 | AF_0623 | DNA repair protein RAD25; Similar to GB:M31899 SP:P19447 PID:182179 percent identity: 32.49; identified by sequence similarity; putative. | DNA ligase (lig); DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.642 |
AF_0358 | pcn | AF_0358 | AF_0335 | DNA repair protein RAD25; Similar to GB:M31899 SP:P19447 PID:182179 percent identity: 32.49; identified by sequence similarity; putative. | Proliferating-cell nuclear antigen (pol30); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.579 |
AF_0358 | pol | AF_0358 | AF_0497 | DNA repair protein RAD25; Similar to GB:M31899 SP:P19447 PID:182179 percent identity: 32.49; identified by sequence similarity; putative. | DNA polymerase B1 (polB); Similar to PID:807830 percent identity: 45.13; identified by sequence similarity; putative. | 0.663 |
AF_0358 | rad50 | AF_0358 | AF_1032 | DNA repair protein RAD25; Similar to GB:M31899 SP:P19447 PID:182179 percent identity: 32.49; identified by sequence similarity; putative. | Purine NTPase, putative; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. | 0.534 |
AF_0580 | fen | AF_0580 | AF_0264 | Exodeoxyribonuclease III (xthA); Similar to PID:1653682 percent identity: 41.31; identified by sequence similarity; putative. | DNA repair protein RAD2 (rad2); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) [...] | 0.989 |
AF_0580 | lig | AF_0580 | AF_0623 | Exodeoxyribonuclease III (xthA); Similar to PID:1653682 percent identity: 41.31; identified by sequence similarity; putative. | DNA ligase (lig); DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.801 |
AF_0580 | mre11 | AF_0580 | AF_1031 | Exodeoxyribonuclease III (xthA); Similar to PID:1653682 percent identity: 41.31; identified by sequence similarity; putative. | DNA repair protein RAD32 (rad32); Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | 0.465 |
AF_0580 | pcn | AF_0580 | AF_0335 | Exodeoxyribonuclease III (xthA); Similar to PID:1653682 percent identity: 41.31; identified by sequence similarity; putative. | Proliferating-cell nuclear antigen (pol30); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.977 |
AF_0580 | pol | AF_0580 | AF_0497 | Exodeoxyribonuclease III (xthA); Similar to PID:1653682 percent identity: 41.31; identified by sequence similarity; putative. | DNA polymerase B1 (polB); Similar to PID:807830 percent identity: 45.13; identified by sequence similarity; putative. | 0.840 |
AF_0580 | polB | AF_0580 | AF_1790 | Exodeoxyribonuclease III (xthA); Similar to PID:1653682 percent identity: 41.31; identified by sequence similarity; putative. | Conserved hypothetical protein; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity); Belongs to the DNA polymerase delta/II small subunit family. | 0.775 |
AF_0580 | rnhB | AF_0580 | AF_0621 | Exodeoxyribonuclease III (xthA); Similar to PID:1653682 percent identity: 41.31; identified by sequence similarity; putative. | Ribonuclease HII (rnhB); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.451 |
AF_2350 | AF_0358 | AF_2350 | AF_0358 | ATP-dependent RNA helicase HepA, putative; Similar to SP:P54509 PID:1303889 GB:AL009126 percent identity: 31.49; identified by sequence similarity; putative. | DNA repair protein RAD25; Similar to GB:M31899 SP:P19447 PID:182179 percent identity: 32.49; identified by sequence similarity; putative. | 0.964 |
AF_2350 | fen | AF_2350 | AF_0264 | ATP-dependent RNA helicase HepA, putative; Similar to SP:P54509 PID:1303889 GB:AL009126 percent identity: 31.49; identified by sequence similarity; putative. | DNA repair protein RAD2 (rad2); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) [...] | 0.991 |
AF_2350 | lig | AF_2350 | AF_0623 | ATP-dependent RNA helicase HepA, putative; Similar to SP:P54509 PID:1303889 GB:AL009126 percent identity: 31.49; identified by sequence similarity; putative. | DNA ligase (lig); DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.670 |
AF_2350 | mre11 | AF_2350 | AF_1031 | ATP-dependent RNA helicase HepA, putative; Similar to SP:P54509 PID:1303889 GB:AL009126 percent identity: 31.49; identified by sequence similarity; putative. | DNA repair protein RAD32 (rad32); Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | 0.883 |
AF_2350 | pcn | AF_2350 | AF_0335 | ATP-dependent RNA helicase HepA, putative; Similar to SP:P54509 PID:1303889 GB:AL009126 percent identity: 31.49; identified by sequence similarity; putative. | Proliferating-cell nuclear antigen (pol30); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.933 |
AF_2350 | pol | AF_2350 | AF_0497 | ATP-dependent RNA helicase HepA, putative; Similar to SP:P54509 PID:1303889 GB:AL009126 percent identity: 31.49; identified by sequence similarity; putative. | DNA polymerase B1 (polB); Similar to PID:807830 percent identity: 45.13; identified by sequence similarity; putative. | 0.855 |
AF_2350 | rad50 | AF_2350 | AF_1032 | ATP-dependent RNA helicase HepA, putative; Similar to SP:P54509 PID:1303889 GB:AL009126 percent identity: 31.49; identified by sequence similarity; putative. | Purine NTPase, putative; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. | 0.722 |