Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AF_0265Molybdenum cofactor biosynthesis protein (moaB); Similar to GB:L77117 PID:1592270 percent identity: 44.44; identified by sequence similarity; putative. (170 aa)    
Predicted Functional Partners:
moaC
Molybdenum cofactor biosynthesis protein (moaC); Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
 0.993
AF_2179
Molybdopterin converting factor, subunit 2 (moaE); Similar to PID:1001216 PID:1001213 percent identity: 33.33; identified by sequence similarity; putative.
 
 
 0.987
AF_0930
Molybdenum cofactor biosynthesis protein (moeA-2); Similar to GB:L77117 SP:Q58080 PID:1591380 percent identity: 44.81; identified by sequence similarity; putative.
 
 0.981
AF_0931
Molybdenum cofactor biosynthesis protein (moeA-1); Similar to GB:L77117 SP:Q58296 PID:1591564 percent identity: 50.83; identified by sequence similarity; putative.
 
 0.974
moaA
Molybdenum cofactor biosynthesis protein (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
 
  
 0.919
AF_0161
Molybdenum cofactor biosynthesis protein (moeA-3); Similar to PID:1001216 PID:1001210 percent identity: 30.50; identified by sequence similarity; putative.
 
 
 0.817
fen
DNA repair protein RAD2 (rad2); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) [...]
       0.817
AF_1624
Molybdopterin converting factor, subunit 1 (moaD); Similar to SP:P30748 PID:42011 GB:U00096 PID:1651357 PID:1787002 percent identity: 36.59; identified by sequence similarity; putative.
  
  
 0.694
cdc6-2
Conserved hypothetical protein; Involved in regulation of DNA replication.
       0.681
dtdA
Conserved hypothetical protein; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
       0.624
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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