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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0265Molybdenum cofactor biosynthesis protein (moaB); Similar to GB:L77117 PID:1592270 percent identity: 44.44; identified by sequence similarity; putative. (170 aa)    
Predicted Functional Partners:
AF_2179
Molybdopterin converting factor, subunit 2 (moaE); Similar to PID:1001216 PID:1001213 percent identity: 33.33; identified by sequence similarity; putative.
 
 
 0.992
moaC
Molybdenum cofactor biosynthesis protein (moaC); Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
 0.990
AF_0930
Molybdenum cofactor biosynthesis protein (moeA-2); Similar to GB:L77117 SP:Q58080 PID:1591380 percent identity: 44.81; identified by sequence similarity; putative.
 
 0.980
AF_0931
Molybdenum cofactor biosynthesis protein (moeA-1); Similar to GB:L77117 SP:Q58296 PID:1591564 percent identity: 50.83; identified by sequence similarity; putative.
 
 0.976
moaA
Molybdenum cofactor biosynthesis protein (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
 
  
 0.918
fen
DNA repair protein RAD2 (rad2); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) [...]
       0.844
AF_0161
Molybdenum cofactor biosynthesis protein (moeA-3); Similar to PID:1001216 PID:1001210 percent identity: 30.50; identified by sequence similarity; putative.
 
 
 0.815
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
     
 0.741
AF_2253
Molybdopterin-guanine dinucleotide biosynthesis protein B (mobB); Similar to GB:L77117 PID:1591964 percent identity: 40.00; identified by sequence similarity; putative.
 
 
 
 0.738
AF_2005
Molybdopterin-guanine dinucleotide biosynthesis protein A (mobA); Similar to GB:L77117 PID:1592243 percent identity: 33.16; identified by sequence similarity; putative.
 
  
 0.615
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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