Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0280Conserved hypothetical protein; Similar to GB:L77117 SP:Q58074 PID:1591373 percent identity: 46.88; identified by sequence similarity; putative. (71 aa)    
Predicted Functional Partners:
AF_1247
Conserved hypothetical protein; Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
       0.580
AF_0279
ISA1214-1, putative transposase; Involved in the transposition of the insertion sequence ISA1214.
       0.551
eif2a
Translation initiation factor eIF-2, subunit alpha (eif2A); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family.
  
 
 
 0.532
AF_1936
Conserved hypothetical protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.
  
     0.515
ef1b
Translation elongation factor EF-1, subunit beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
  
  
 0.506
AF_0849
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57857 PID:1499205 percent identity: 43.16; identified by sequence similarity; putative.
  
     0.501
AF_1294
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58061 PID:1591357 percent identity: 44.97; identified by sequence similarity; putative.
  
     0.471
AF_0243
Conserved hypothetical protein; Similar to GB:L77117 PID:1590999 percent identity: 45.88; identified by sequence similarity; putative.
       0.468
AF_0744
GTP-binding protein; Similar to GP:727171 percent identity: 33.40; identified by sequence similarity; putative.
  
 
 
 0.451
AF_1062
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57905 PID:1591185 percent identity: 57.76; identified by sequence similarity; putative.
  
     0.448
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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