Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0282Conserved hypothetical protein; Similar to GB:L77117 SP:Q60372 PID:1498830 percent identity: 52.63; identified by sequence similarity; putative; Belongs to the UPF0212 family. (113 aa)    
Predicted Functional Partners:
AF_1060
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58960 PID:1500459 percent identity: 33.10; identified by sequence similarity; putative.
       0.681
AF_2118
Inosine monophosphate dehydrogenase (guaB-2); Similar to GB:L77117 SP:Q58069 PID:1592300 percent identity: 31.86; identified by sequence similarity; putative.
       0.624
AF_1666
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57990 PID:1591277 percent identity: 44.14; identified by sequence similarity; putative.
       0.610
dphB
Diphthine synthase (dph5); S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.
       0.603
AF_0210
Predicted coding region AF_0210; Hypothetical protein; identified by GeneMark; putative.
       0.601
AF_0281
Predicted coding region AF_0281; Hypothetical protein; identified by GeneMark; putative.
       0.581
AF_1782
Conserved hypothetical protein; Similar to GB:L77117 PID:1590998 percent identity: 34.72; identified by sequence similarity; putative.
       0.516
AF_0283
3-ketoacyl-CoA thiolase (acaB-7); Similar to GB:L77117 PID:1592180 percent identity: 41.99; identified by sequence similarity; putative.
       0.514
AF_0284
Conserved hypothetical protein; Similar to GB:L77117 PID:1592182 percent identity: 34.34; identified by sequence similarity; putative.
       0.514
AF_0285
3-hydroxyacyl-CoA dehydrogenase (hbd-2); Similar to PID:1055222 SP:P52041 percent identity: 55.79; identified by sequence similarity; putative; Belongs to the enoyl-CoA hydratase/isomerase family.
       0.507
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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