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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AF_0327Conserved hypothetical protein; Similar to PID:1001414 PID:1001478 percent identity: 26.94; identified by sequence similarity; putative. (357 aa)    
Predicted Functional Partners:
AF_0328
dolichol-P-glucose synthetase, putative; Similar to GB:L77117 SP:Q58619 PID:1591853 percent identity: 38.99; identified by sequence similarity; putative.
 
  
 0.893
aglB1
Transmembrane oligosaccharyl transferase, putative; Oligosaccharyl transferase (OST) that catalyzes the initial transfer of a defined glycan (a GalNAc-linked heptasaccharide composed of 4 Hex, 3 dHex and a sulfate for A.fulgidus AglB-S) from the lipid carrier dolichol-monophosphate to an asparagine residue within an Asn- X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation; Belongs to the STT3 family.
     
 0.790
AF_0595
Polysaccharide biosynthesis protein, putative; Similar to GB:L77117 PID:1591720 percent identity: 24.05; identified by sequence similarity; putative.
 
  
 0.646
AF_0039
dolichol-P-glucose synthetase, putative; Similar to GB:L77117 SP:Q58619 PID:1591853 percent identity: 33.68; identified by sequence similarity; putative.
 
  
 0.540
AF_0324
dTDP-glucose 4,6-dehydratase (rfbB); Similar to PID:567874 percent identity: 50.00; identified by sequence similarity; putative.
  
  
 0.531
AF_0325
Glucose-1-phosphate thymidylyltransferase (graD-2); Similar to PID:763512 percent identity: 43.11; identified by sequence similarity; putative.
  
  
 0.531
AF_1563
Conserved hypothetical protein; Similar to SP:P29368 GB:M38048 SP:Q99390 PID:151837 PID:42626 percent identity: 33.94; identified by sequence similarity; putative.
 
 
 
 0.485
AF_0321
Glycosyl transferase; Similar to GP:1666509 percent identity: 30.69; identified by sequence similarity; putative.
 
  
 0.453
topA
DNA topoisomerase I (topA); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing D [...]
 
 
 
 0.424
AF_0675
2-hydroxy-6-oxohepta-2,4-dienoate hydrolase (todF); Similar to GB:M64080 SP:P23133 GB:U18304 PID:151222 percent identity: 26.35; identified by sequence similarity; putative.
   
 
 0.418
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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