Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0331Pheromone shutdown protein (traB); Similar to GB:L77117 PID:1592009 percent identity: 40.48; identified by sequence similarity; putative. (396 aa)    
Predicted Functional Partners:
AF_0332
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57837 PID:1592287 percent identity: 42.18; identified by sequence similarity; putative; Belongs to the peptidase M50B family.
       0.906
amzA
Conserved hypothetical protein; Probable zinc metalloprotease whose natural substrate is unknown.
       0.773
rnhB
Ribonuclease HII (rnhB); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
   
   0.663
AF_0682
Succinate dehydrogenase, iron-sulfur subunit B (sdhB); Similar to GB:X70908 PID:396212 percent identity: 51.27; identified by sequence similarity; putative.
    
   0.651
rnz
Conserved hypothetical protein; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
       0.624
purM
Phosphoribosylformylglycinamidine cyclo-ligase (purM); Similar to GB:L77117 SP:Q57656 PID:1590946 percent identity: 53.77; identified by sequence similarity; putative.
       0.613
AF_1494
Predicted coding region AF_1494; Hypothetical protein; identified by GeneMark; putative.
 
     0.583
AF_0333
4-hydroxyphenylacetate-3-hydroxylase (hpaA-1); Similar to PID:974146 percent identity: 22.35; identified by sequence similarity; putative.
       0.536
AF_0334
Predicted coding region AF_0334; Hypothetical protein; identified by GeneMark; putative.
       0.536
AF_1652
Prepro-subtilisin sendai, putative; Similar to PID:995964 percent identity: 35.59; identified by sequence similarity; putative.
   
   0.502
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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