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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0345Predicted coding region AF_0345; Hypothetical protein; identified by GeneMark; putative. (164 aa)    
Predicted Functional Partners:
rpiA
Ribose 5-phosphate isomerase (rpi); Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
  
    0.743
AF_0343
Tryptophan repressor binding protein (wrbA); It seems to function in response to environmental stress when various electron transfer chains are affected or when the environment is highly oxidizing. It reduces quinones to the hydroquinone state to prevent interaction of the semiquinone with O2 and production of superoxide. It prefers NADH over NADPH; Belongs to the WrbA family.
  
    0.535
copZ
Mercuric transport protein periplasmic component (merP); Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) directly to the transmembrane transport sites of copper-exporting P-type ATPase A (CopA). Probably has a redox function due to the presence of a 2Fe-2S cluster and could reduce Cu(2+) to Cu(+).
       0.504
AF_0344
Desulfoferrodoxin, putative; Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide.
       0.492
AF_0349
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57997 PID:1591284 percent identity: 40.96; identified by sequence similarity; putative.
  
  
 0.479
AF_2151
Isochorismatase (entB); Similar to PID:1045016 SP:Q51790 percent identity: 31.21; identified by sequence similarity; putative.
  
    0.458
AF_2335
Conserved hypothetical protein; Similar to GP:1200033 percent identity: 39.64; identified by sequence similarity; putative.
  
    0.458
ndk
Nucleoside diphosphate kinase (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
     
 0.436
AF_1901
Conserved hypothetical transmembrane protein; Similar to GB:L77117 SP:Q57904 PID:1591183 percent identity: 27.49; identified by sequence similarity; putative.
   
    0.422
ppaC
Exopolyphosphatase (ppx1); Similar to GB:L77117 SP:Q58025 PID:1591318 percent identity: 55.12; identified by sequence similarity; putative.
  
    0.410
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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