Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AF_0356Carbohydrate kinase, pfkB family; Similar to SP:P36945 GB:Z25798 PID:397495 PID:1894761 GB:AL009126 percent identity: 31.28; identified by sequence similarity; putative; Belongs to the carbohydrate kinase PfkB family. (250 aa)    
Predicted Functional Partners:
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (hisA-2); Similar to GB:L77117 SP:Q58927 PID:1592163 percent identity: 42.24; identified by sequence similarity; putative.
  
    0.837
purA
Adenylosuccinate synthetase (purA); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.764
rps11
SSU ribosomal protein S11P (rps11P); Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
  
 
 0.646
AF_1968
Transcriptional regulatory protein, Rok family; Similar to PID:1208894 SP:Q44406 percent identity: 32.91; identified by sequence similarity; putative.
 
  
 0.606
AF_1886
DNA-directed RNA polymerase, subunit B'' (rpoB2); Similar to SP:P15352 PID:43540 percent identity: 57.14; identified by sequence similarity; putative; Belongs to the RNA polymerase beta chain family.
  
 
 0.562
rpoB1
DNA-directed RNA polymerase, subunit B' (rpoB1); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The B (B''+B' and beta) subunits have been implicated in DNA promoter recognition and also in nucleotide binding.
  
 
 0.562
tpiA
Triosephosphate isomerase (tpiA); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
  
 0.550
purB
Adenylosuccinate lyase (purB); Similar to GB:L77117 PID:1591600 percent identity: 52.27; identified by sequence similarity; putative.
  
 
 0.533
AF_2101
Alcohol dehydrogenase, zinc-dependent; Similar to GB:M96947 SP:Q06004 PID:304153 GB:AL009126 percent identity: 30.06; identified by sequence similarity; putative.
 
  
 0.512
gap
Glyceraldehyde 3-phosphate dehydrogenase (gap); Similar to SP:P10618 PID:149792 percent identity: 56.59; identified by sequence similarity; putative.
  
  
 0.508
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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