close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0366acetyl-CoA synthetase (acs-2); Similar to PID:1001216 PID:1001254 percent identity: 47.28; identified by sequence similarity; putative. (681 aa)    
Predicted Functional Partners:
AF_1340
Citrate synthase (citZ); Similar to GB:U05257 SP:P39120 PID:487433 PID:2293267 GB:AL009126 percent identity: 50.27; identified by sequence similarity; putative.
  
 0.981
AF_0018
3-ketoacyl-CoA thiolase (acaB-1); Similar to GB:L77117 PID:1592180 percent identity: 41.02; identified by sequence similarity; putative.
  
 
 0.965
AF_0133
3-ketoacyl-CoA thiolase (acaB-3); Similar to GB:L77117 PID:1592180 percent identity: 32.33; identified by sequence similarity; putative.
  
 
 0.965
AF_0283
3-ketoacyl-CoA thiolase (acaB-7); Similar to GB:L77117 PID:1592180 percent identity: 41.99; identified by sequence similarity; putative.
  
 
 0.965
AF_0438
3-ketoacyl-CoA thiolase (acaB-8); Similar to GB:L77117 PID:1592180 percent identity: 42.41; identified by sequence similarity; putative.
  
 
 0.965
AF_0968
3-ketoacyl-CoA thiolase (acaB-10); Similar to GB:L77117 PID:1592180 percent identity: 27.98; identified by sequence similarity; putative.
  
 
 0.965
AF_1028
3-ketoacyl-CoA thiolase (fadA-1); Similar to GP:1742272 percent identity: 38.83; identified by sequence similarity; putative.
  
 
 0.965
AF_2416
3-ketoacyl-CoA thiolase (acaB-12); Similar to GB:L77117 PID:1592180 percent identity: 49.87; identified by sequence similarity; putative.
  
 
 0.965
AF_1938
Conserved hypothetical protein; Catalyzes the reversible conversion of a variety of acids to the corresponding acyl-CoA esters. Shows the highest activity with the aryl acids, indoleacetate and phenylacetate, as compared to acetate. In the reverse direction, phenylacetyl-CoA is the best substrate. Seems to be involved primarily in the degradation of aryl-CoA esters to the corresponding acids. Participates in the degradation of branched-chain amino acids via branched-chain-acyl-CoA esters. In the C-terminal section; belongs to the acetate CoA ligase alpha subunit family.
    
 0.956
cdhE
acetyl-CoA decarbonylase/synthase, subunit gamma (cdhE); Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).
   
 
 0.950
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.