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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
oggConserved hypothetical protein; Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites) (By similarity); Belongs to the type-2 OGG1 family. (198 aa)    
Predicted Functional Partners:
AF_0372
Conserved hypothetical protein; Similar to GB:Z35277 SP:P39756 PID:580895 PID:1648855 GB:AL009126 percent identity: 30.16; identified by sequence similarity; putative.
       0.776
AF_0370
Translation initiation factor eIF-2B, subunit delta (eif2BD); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
       0.773
AF_0369
Predicted coding region AF_0369; Hypothetical protein; identified by GeneMark; putative.
       0.682
priS
DNA primase, putative; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May [...]
       0.534
AF_1332
Predicted coding region AF_1332; Hypothetical protein; identified by GeneMark; putative.
       0.534
rpl44e
LSU ribosomal protein L44E (rpl44E); Binds to the 23S rRNA.
       0.534
rps27e
SSU ribosomal protein S27E (rps27E); Similar to GB:L77117 SP:P54028 PID:1499029 percent identity: 49.02; identified by sequence similarity; putative.
       0.534
AF_1356
Phosphate ABC transporter, periplasmic phosphate-binding protein (phoX); Similar to PID:1052826 percent identity: 25.09; identified by sequence similarity; putative.
     
 0.436
AF_2307
Predicted coding region AF_2307; Hypothetical protein; identified by GeneMark; putative.
      
 0.429
cbiHC
Cobalamin biosynthesis precorrin-3 methylase (cbiH); Bifunctional enzyme with a methyltransferase domain that catalyzes the ring contraction and methylation of C-17 in cobalt-factor III to form cobalt-factor IV, and an isomerase domain that catalyzes the conversion of cobalt-precorrin-8 to cobyrinate; In the C-terminal section; belongs to the CobH family.
       0.428
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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