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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0372Conserved hypothetical protein; Similar to GB:Z35277 SP:P39756 PID:580895 PID:1648855 GB:AL009126 percent identity: 30.16; identified by sequence similarity; putative. (227 aa)    
Predicted Functional Partners:
moaA
Molybdenum cofactor biosynthesis protein (moaA); Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
 
  
 0.837
iscS1
nifS protein, class-V aminotransferase (nifS-1); Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
 
 0.789
iscS2
nifS protein, class-V aminotransferase (nifS-2); Catalyzes the removal of elemental sulfur from cysteine to produce alanine (Probable). Binds 1 2Fe-2S cluster per subunit in a crystal formed under reducing conditions; this subunit provides 1 ligand while IscU provides the other 3 ligands. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
 
 0.788
AF_2005
Molybdopterin-guanine dinucleotide biosynthesis protein A (mobA); Similar to GB:L77117 PID:1592243 percent identity: 33.16; identified by sequence similarity; putative.
 
 
 
 0.781
ogg
Conserved hypothetical protein; Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites) (By similarity); Belongs to the type-2 OGG1 family.
       0.776
AF_0370
Translation initiation factor eIF-2B, subunit delta (eif2BD); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
       0.773
moaC
Molybdenum cofactor biosynthesis protein (moaC); Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
  
 0.733
AF_1929
Tungsten formylmethanofuran dehydrogenase, subunit B (fwdB-2); Similar to GP:1781026 percent identity: 49.40; identified by sequence similarity; putative.
 
   
 0.689
AF_0369
Predicted coding region AF_0369; Hypothetical protein; identified by GeneMark; putative.
       0.682
AF_2253
Molybdopterin-guanine dinucleotide biosynthesis protein B (mobB); Similar to GB:L77117 PID:1591964 percent identity: 40.00; identified by sequence similarity; putative.
 
  
 0.670
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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