node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AF_0058 | AF_2088 | AF_0058 | AF_2088 | Conserved hypothetical protein; Similar to GB:L77117 PID:1592059 percent identity: 36.08; identified by sequence similarity; putative; Belongs to the UPF0113 family. | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58105 PID:1591409 percent identity: 38.19; identified by sequence similarity; putative. | 0.939 |
AF_0058 | AF_2402 | AF_0058 | AF_2402 | Conserved hypothetical protein; Similar to GB:L77117 PID:1592059 percent identity: 36.08; identified by sequence similarity; putative; Belongs to the UPF0113 family. | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58536 PID:1591770 percent identity: 51.68; identified by sequence similarity; putative. | 0.670 |
AF_0058 | dphB | AF_0058 | AF_0381 | Conserved hypothetical protein; Similar to GB:L77117 PID:1592059 percent identity: 36.08; identified by sequence similarity; putative; Belongs to the UPF0113 family. | Diphthine synthase (dph5); S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. | 0.676 |
AF_0382 | aglB3 | AF_0382 | AF_0380 | Conserved hypothetical protein; Similar to GB:L77117 PID:1500014 percent identity: 26.69; identified by sequence similarity; putative. | Transmembrane oligosaccharyl transferase, putative; Oligosaccharyl transferase (OST) that catalyzes the initial transfer of a defined glycan (a glucose-linked heptasaccharide composed of 3 Glc, 2 Man, 2 Gal and a sulfate for A.fulgidus AglB-L) from the lipid carrier dolichol-monophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation; Belongs to the STT3 family. | 0.535 |
AF_0382 | dphB | AF_0382 | AF_0381 | Conserved hypothetical protein; Similar to GB:L77117 PID:1500014 percent identity: 26.69; identified by sequence similarity; putative. | Diphthine synthase (dph5); S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. | 0.714 |
AF_0720 | dphB | AF_0720 | AF_0381 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57990 PID:1591277 percent identity: 33.33; identified by sequence similarity; putative. | Diphthine synthase (dph5); S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. | 0.710 |
AF_0720 | fusA | AF_0720 | AF_1894 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57990 PID:1591277 percent identity: 33.33; identified by sequence similarity; putative. | Translation elongation factor EF-2 (fus); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor G [...] | 0.782 |
AF_1666 | AF_1803 | AF_1666 | AF_1803 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57990 PID:1591277 percent identity: 44.14; identified by sequence similarity; putative. | Conserved hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | 0.529 |
AF_1666 | dphB | AF_1666 | AF_0381 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57990 PID:1591277 percent identity: 44.14; identified by sequence similarity; putative. | Diphthine synthase (dph5); S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. | 0.664 |
AF_1666 | fusA | AF_1666 | AF_1894 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57990 PID:1591277 percent identity: 44.14; identified by sequence similarity; putative. | Translation elongation factor EF-2 (fus); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor G [...] | 0.793 |
AF_1803 | AF_1666 | AF_1803 | AF_1666 | Conserved hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Conserved hypothetical protein; Similar to GB:L77117 SP:Q57990 PID:1591277 percent identity: 44.14; identified by sequence similarity; putative. | 0.529 |
AF_1803 | AF_2088 | AF_1803 | AF_2088 | Conserved hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58105 PID:1591409 percent identity: 38.19; identified by sequence similarity; putative. | 0.498 |
AF_1803 | AF_2402 | AF_1803 | AF_2402 | Conserved hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58536 PID:1591770 percent identity: 51.68; identified by sequence similarity; putative. | 0.590 |
AF_1803 | dphB | AF_1803 | AF_0381 | Conserved hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Diphthine synthase (dph5); S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. | 0.918 |
AF_1803 | eif2b | AF_1803 | AF_2326 | Conserved hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Translation initiation factor eIF-2, subunit beta, putative; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-beta/eIF-5 family. | 0.591 |
AF_1803 | fusA | AF_1803 | AF_1894 | Conserved hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Translation elongation factor EF-2 (fus); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor G [...] | 0.986 |
AF_2088 | AF_0058 | AF_2088 | AF_0058 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58105 PID:1591409 percent identity: 38.19; identified by sequence similarity; putative. | Conserved hypothetical protein; Similar to GB:L77117 PID:1592059 percent identity: 36.08; identified by sequence similarity; putative; Belongs to the UPF0113 family. | 0.939 |
AF_2088 | AF_1803 | AF_2088 | AF_1803 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58105 PID:1591409 percent identity: 38.19; identified by sequence similarity; putative. | Conserved hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | 0.498 |
AF_2088 | AF_2402 | AF_2088 | AF_2402 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58105 PID:1591409 percent identity: 38.19; identified by sequence similarity; putative. | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58536 PID:1591770 percent identity: 51.68; identified by sequence similarity; putative. | 0.419 |
AF_2088 | dphB | AF_2088 | AF_0381 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58105 PID:1591409 percent identity: 38.19; identified by sequence similarity; putative. | Diphthine synthase (dph5); S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. | 0.636 |