Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dldD-lactate dehydrogenase, cytochrome-type (dld); Converts D-lactate to pyruvate. Cannot use NAD(+), cytochrome C, methylene blue or dimethylnaphthoquinone as acceptors. Active in vitro with artificial electron acceptors such as 2,6- dichlorophenolindophenol, but the physiological acceptor is not yet known. (443 aa)    
Predicted Functional Partners:
AF_1727
Malate oxidoreductase (mae); Similar to GP:1006839 percent identity: 52.30; identified by sequence similarity; putative.
  
 
 0.937
pycA
Biotin carboxylase (acc); Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.930
korB
2-ketoglutarate ferredoxin oxidoreductase, subunit beta (korB); Similar to GB:L77117 PID:1591241 percent identity: 51.38; identified by sequence similarity; putative.
    
 0.925
AF_1252
Oxaloacetate decarboxylase, subunit alpha (oadA); Similar to GB:L77117 PID:1591862 percent identity: 63.26; identified by sequence similarity; putative.
    
 0.925
AF_1699
Pyruvate ferredoxin oxidoreductase, subunit gamma (porG); Similar to PID:1197358 percent identity: 50.84; identified by sequence similarity; putative.
    
 0.925
AF_2084
Oxaloacetate decarboxylase, sodium ion pump subunit (oadB); Similar to GB:M96434 SP:Q03031 PID:154198 percent identity: 59.83; identified by sequence similarity; putative.
    
  0.902
korA
2-ketoglutarate ferredoxin oxidoreductase, subunit alpha (korA); Similar to GB:L77117 PID:1592279 percent identity: 52.34; identified by sequence similarity; putative.
    
 0.901
AF_0749
2-oxoacid ferredoxin oxidoreductase, subunit alpha (orA); Similar to GP:1565183 percent identity: 33.70; identified by sequence similarity; putative.
    
 0.901
AF_0750
2-oxoacid ferredoxin oxidoreductase, subunit beta (orB); Similar to GP:1565184 percent identity: 49.21; identified by sequence similarity; putative.
    
  0.901
AF_1701
Pyruvate ferredoxin oxidoreductase, subunit alpha (porA); Similar to PID:1590995 percent identity: 50.27; identified by sequence similarity; putative.
    
 0.901
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.