Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AF_0395NADH oxidase (noxA-2); Similar to GB:L77117 SP:Q58065 PID:1591361 percent identity: 35.45; identified by sequence similarity; putative. (436 aa)    
Predicted Functional Partners:
hmeD
Heterodisulfide reductase, subunit D, putative; Has menaquinol-oxidizing activity. HmeC and HmeD subunits may together mediate electron transfer from menaquinol to an unidentified electron acceptor on the cytoplasmic side of the membrane.
  
 
 0.910
AF_0254
NADH oxidase (noxA-1); Similar to GB:L77117 SP:Q58065 PID:1591361 percent identity: 35.14; identified by sequence similarity; putative.
  
  
 
0.903
AF_0557
Flavoprotein reductase; Similar to GP:1480407 percent identity: 26.19; identified by sequence similarity; putative.
    
  0.903
hmeA
Molybdopterin oxidoreductase, iron-sulfur binding subunit; Has menaquinol-oxidizing activity. HmeA, HmeB and HmeE subunits may together catalyze electron transfer from menaquinol to cytochrome c.
    
  0.901
hmeC
Nitrate reductase, gamma subunit, putative; Has menaquinol-oxidizing activity. HmeC and HmeD subunits may together mediate electron transfer from menaquinol to an unidentified electron acceptor on the cytoplasmic side of the membrane.
    
  0.901
AF_0546
Nitrate reductase, gamma subunit (narI); Similar to GB:Z26255 percent identity: 30.14; identified by sequence similarity; putative.
    
  0.901
hmeB
Molybdopterin oxidoreductase, membrane subunit; Has menaquinol-oxidizing activity. HmeB subunit may function as a menaquinol-oxidizing site. HmeA, HmeB and HmeE subunits may together catalyze electron transfer from menaquinol to cytochrome c.
    
  0.900
hmeE
Predicted coding region AF_0503; Has menaquinol-oxidizing activity. HmeA, HmeB and HmeE subunits may together catalyze electron transfer from menaquinol to cytochrome c.
     
  0.900
AF_0167
Flavoprotein (fprA-1); Similar to GB:L77117 SP:Q58142 PID:1591446 percent identity: 33.23; identified by sequence similarity; putative.
    
 0.893
dld
D-lactate dehydrogenase, cytochrome-type (dld); Converts D-lactate to pyruvate. Cannot use NAD(+), cytochrome C, methylene blue or dimethylnaphthoquinone as acceptors. Active in vitro with artificial electron acceptors such as 2,6- dichlorophenolindophenol, but the physiological acceptor is not yet known.
  
  
 0.865
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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