node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AF_0401 | AF_0402 | AF_0401 | AF_0402 | Carbohydrate kinase, pfkB family; Similar to SP:P40713 PID:608707 percent identity: 34.10; identified by sequence similarity; putative. | Predicted coding region AF_0402; Hypothetical protein; identified by GeneMark; putative. | 0.718 |
AF_0401 | AF_0403 | AF_0401 | AF_0403 | Carbohydrate kinase, pfkB family; Similar to SP:P40713 PID:608707 percent identity: 34.10; identified by sequence similarity; putative. | Conserved hypothetical protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. To a much lesser extent, is also able to use heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) as the prenyl donor. Belongs to the GGGP/HepGP synthase family. Group I subfamily. | 0.598 |
AF_0401 | AF_0404 | AF_0401 | AF_0404 | Carbohydrate kinase, pfkB family; Similar to SP:P40713 PID:608707 percent identity: 34.10; identified by sequence similarity; putative. | 4-hydroxybenzoate octaprenyltransferase, putative; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.598 |
AF_0401 | tpiA | AF_0401 | AF_1304 | Carbohydrate kinase, pfkB family; Similar to SP:P40713 PID:608707 percent identity: 34.10; identified by sequence similarity; putative. | Triosephosphate isomerase (tpiA); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.505 |
AF_0402 | AF_0401 | AF_0402 | AF_0401 | Predicted coding region AF_0402; Hypothetical protein; identified by GeneMark; putative. | Carbohydrate kinase, pfkB family; Similar to SP:P40713 PID:608707 percent identity: 34.10; identified by sequence similarity; putative. | 0.718 |
AF_0402 | AF_0403 | AF_0402 | AF_0403 | Predicted coding region AF_0402; Hypothetical protein; identified by GeneMark; putative. | Conserved hypothetical protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. To a much lesser extent, is also able to use heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) as the prenyl donor. Belongs to the GGGP/HepGP synthase family. Group I subfamily. | 0.642 |
AF_0402 | AF_0404 | AF_0402 | AF_0404 | Predicted coding region AF_0402; Hypothetical protein; identified by GeneMark; putative. | 4-hydroxybenzoate octaprenyltransferase, putative; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.642 |
AF_0403 | AF_0401 | AF_0403 | AF_0401 | Conserved hypothetical protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. To a much lesser extent, is also able to use heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) as the prenyl donor. Belongs to the GGGP/HepGP synthase family. Group I subfamily. | Carbohydrate kinase, pfkB family; Similar to SP:P40713 PID:608707 percent identity: 34.10; identified by sequence similarity; putative. | 0.598 |
AF_0403 | AF_0402 | AF_0403 | AF_0402 | Conserved hypothetical protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. To a much lesser extent, is also able to use heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) as the prenyl donor. Belongs to the GGGP/HepGP synthase family. Group I subfamily. | Predicted coding region AF_0402; Hypothetical protein; identified by GeneMark; putative. | 0.642 |
AF_0403 | AF_0404 | AF_0403 | AF_0404 | Conserved hypothetical protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. To a much lesser extent, is also able to use heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) as the prenyl donor. Belongs to the GGGP/HepGP synthase family. Group I subfamily. | 4-hydroxybenzoate octaprenyltransferase, putative; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.998 |
AF_0403 | AF_0866 | AF_0403 | AF_0866 | Conserved hypothetical protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. To a much lesser extent, is also able to use heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) as the prenyl donor. Belongs to the GGGP/HepGP synthase family. Group I subfamily. | Glycerol kinase (glpK); Similar to GB:M34393 SP:P18157 PID:142992 PID:2226137 GB:AL009126 percent identity: 33.83; identified by sequence similarity; putative; Belongs to the FGGY kinase family. | 0.853 |
AF_0403 | AF_1551 | AF_0403 | AF_1551 | Conserved hypothetical protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. To a much lesser extent, is also able to use heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) as the prenyl donor. Belongs to the GGGP/HepGP synthase family. Group I subfamily. | Octaprenyl-diphosphate synthase (ispB); Similar to GB:L42023 SP:P44916 PID:1005963 PID:1220984 PID:1205128 percent identity: 33.20; identified by sequence similarity; putative; Belongs to the FPP/GGPP synthase family. | 0.715 |
AF_0403 | carS | AF_0403 | AF_1740 | Conserved hypothetical protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. To a much lesser extent, is also able to use heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) as the prenyl donor. Belongs to the GGGP/HepGP synthase family. Group I subfamily. | Conserved hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. Can use CTP or dCTP, but not ATP, GTP or TTP; Belongs to the CDP-archaeol synthase family. | 0.671 |
AF_0403 | egsA | AF_0403 | AF_1674 | Conserved hypothetical protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. To a much lesser extent, is also able to use heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) as the prenyl donor. Belongs to the GGGP/HepGP synthase family. Group I subfamily. | Sn-glycerol-1-phosphate dehydrogenase (gldA); Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family. | 0.986 |
AF_0403 | gpsA | AF_0403 | AF_0871 | Conserved hypothetical protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. To a much lesser extent, is also able to use heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) as the prenyl donor. Belongs to the GGGP/HepGP synthase family. Group I subfamily. | Glycerol-3-phosphate dehydrogenase (NAD(P)+) (gpsA); Similar to SP:P46919 PID:974332 PID:1146220 GB:AL009126 percent identity: 36.31; identified by sequence similarity; putative. | 0.838 |
AF_0403 | tpiA | AF_0403 | AF_1304 | Conserved hypothetical protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. To a much lesser extent, is also able to use heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) as the prenyl donor. Belongs to the GGGP/HepGP synthase family. Group I subfamily. | Triosephosphate isomerase (tpiA); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.920 |
AF_0403 | uppS | AF_0403 | AF_1219 | Conserved hypothetical protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. To a much lesser extent, is also able to use heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) as the prenyl donor. Belongs to the GGGP/HepGP synthase family. Group I subfamily. | Conserved hypothetical protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. | 0.532 |
AF_0404 | AF_0401 | AF_0404 | AF_0401 | 4-hydroxybenzoate octaprenyltransferase, putative; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Carbohydrate kinase, pfkB family; Similar to SP:P40713 PID:608707 percent identity: 34.10; identified by sequence similarity; putative. | 0.598 |
AF_0404 | AF_0402 | AF_0404 | AF_0402 | 4-hydroxybenzoate octaprenyltransferase, putative; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Predicted coding region AF_0402; Hypothetical protein; identified by GeneMark; putative. | 0.642 |
AF_0404 | AF_0403 | AF_0404 | AF_0403 | 4-hydroxybenzoate octaprenyltransferase, putative; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Conserved hypothetical protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. To a much lesser extent, is also able to use heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) as the prenyl donor. Belongs to the GGGP/HepGP synthase family. Group I subfamily. | 0.998 |