STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kptA1Conserved hypothetical protein; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase (By similarity). (216 aa)    
Predicted Functional Partners:
AF_0407
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57677 PID:1499001 percent identity: 48.72; identified by sequence similarity; putative.
       0.786
AF_0408
Predicted coding region AF_0408; Hypothetical protein; identified by GeneMark; putative.
       0.773
AF_0409
Aspartate aminotransferase (aspB-4); Similar to PID:1001492 PID:1001578 percent identity: 45.24; identified by sequence similarity; putative.
  
    0.568
AF_1431
Predicted coding region AF_1431; Hypothetical protein; identified by GeneMark; putative.
       0.534
AF_1432
Conserved hypothetical protein; Similar to SP:P38331 PID:536651 percent identity: 30.26; identified by sequence similarity; putative.
       0.534
AF_1521
Conserved hypothetical protein; Removes ADP-ribose from asparatate and glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Catalyzes removal of a phosphate group from ADP-ribose 1''-phosphate (Appr1p), but with low efficiency.
 
  
 0.469
AF_0410
Signal-transducing histidine kinase, putative; Similar to PID:1652841 percent identity: 27.88; identified by sequence similarity; putative.
  
    0.456
AF_1724
Dinitrogenase reductase activating glycohydrolase (draG); Similar to GB:L77117 PID:1591815 percent identity: 37.92; identified by sequence similarity; putative; Belongs to the ADP-ribosylglycohydrolase family.
 
   
 0.454
rtcA
Conserved hypothetical protein; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity).
 
   
 0.408
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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