Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dsrASulfite reductase, subunit alpha (dsrA); Catalyzes the reduction of sulfite to sulfide. This is the terminal oxidation reaction in sulfate respiration. (418 aa)    
Predicted Functional Partners:
dsrB
Sulfite reductase, subunit beta (dsrB); Catalyzes the reduction of sulfite to sulfide. This is the terminal oxidation reaction in sulfate respiration.
 
 
0.998
hmeD
Heterodisulfide reductase, subunit D, putative; Has menaquinol-oxidizing activity. HmeC and HmeD subunits may together mediate electron transfer from menaquinol to an unidentified electron acceptor on the cytoplasmic side of the membrane.
 
 
 0.983
hmeE
Predicted coding region AF_0503; Has menaquinol-oxidizing activity. HmeA, HmeB and HmeE subunits may together catalyze electron transfer from menaquinol to cytochrome c.
 
 
 0.975
hmeC
Nitrate reductase, gamma subunit, putative; Has menaquinol-oxidizing activity. HmeC and HmeD subunits may together mediate electron transfer from menaquinol to an unidentified electron acceptor on the cytoplasmic side of the membrane.
 
  
 0.973
AF_0546
Nitrate reductase, gamma subunit (narI); Similar to GB:Z26255 percent identity: 30.14; identified by sequence similarity; putative.
 
  
 0.972
hmeB
Molybdopterin oxidoreductase, membrane subunit; Has menaquinol-oxidizing activity. HmeB subunit may function as a menaquinol-oxidizing site. HmeA, HmeB and HmeE subunits may together catalyze electron transfer from menaquinol to cytochrome c.
 
 
 0.970
AF_1669
Adenylylsulfate reductase, subunit B (aprB); Similar to GB:X63435 PID:443816 GB:AE000782 percent identity: 100.00; identified by sequence similarity; putative.
 
 
 0.970
AF_1670
Adenylylsulfate reductase, subunit A (aprA); Similar to GB:X63435 PID:38809 percent identity: 95.98; identified by sequence similarity; putative.
 
 
 0.965
hmeA
Molybdopterin oxidoreductase, iron-sulfur binding subunit; Has menaquinol-oxidizing activity. HmeA, HmeB and HmeE subunits may together catalyze electron transfer from menaquinol to cytochrome c.
 
 
 0.953
cooS
Carbon monoxide dehydrogenase, catalytic subunit (cooS); CODH oxidizes carbon monoxide coupled, via CooF, to the reduction of a hydrogen cation by a hydrogenase (possibly CooH).
     
 0.937
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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