Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_04343-hydroxyacyl-CoA dehydrogenase (hbd-3); Similar to GB:M31799 PID:144733 percent identity: 40.73; identified by sequence similarity; putative. (304 aa)    
Predicted Functional Partners:
AF_0435
enoyl-CoA hydratase (fad-1); Similar to PID:755067 percent identity: 47.64; identified by sequence similarity; putative; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.988
AF_0963
enoyl-CoA hydratase (fad-3); Similar to PID:755067 percent identity: 48.56; identified by sequence similarity; putative; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.949
AF_0438
3-ketoacyl-CoA thiolase (acaB-8); Similar to GB:L77117 PID:1592180 percent identity: 42.41; identified by sequence similarity; putative.
  
 0.926
AF_0436
acyl-CoA dehydrogenase (acd-2); Similar to SP:P45867 PID:853760 GB:AL009126 percent identity: 44.06; identified by sequence similarity; putative.
  
 0.911
AF_0685
enoyl-CoA hydratase (fad-2); Similar to PID:755067 percent identity: 39.92; identified by sequence similarity; putative; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.852
AF_0437
Conserved hypothetical protein; Similar to GB:L77117 PID:1592182 percent identity: 32.98; identified by sequence similarity; putative.
       0.775
AF_0991
glutaryl-CoA dehydrogenase (gcdH); Similar to GB:U69141 SP:Q92947 PID:1549327 PID:1905909 PID:2316112 percent identity: 48.68; identified by sequence similarity; putative.
 0.746
AF_1028
3-ketoacyl-CoA thiolase (fadA-1); Similar to GP:1742272 percent identity: 38.83; identified by sequence similarity; putative.
  
 0.693
AF_1197
3-ketoacyl-CoA thiolase (fadA-2); Similar to GB:U08465 SP:P45359 PID:475715 percent identity: 57.95; identified by sequence similarity; putative.
  
 0.693
AF_2243
3-ketoacyl-CoA thiolase (fadA-3); Similar to GB:M87049 SP:P21151 GB:M59368 GB:M74164 PID:145901 percent identity: 40.83; identified by sequence similarity; putative.
  
 0.693
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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