Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_04383-ketoacyl-CoA thiolase (acaB-8); Similar to GB:L77117 PID:1592180 percent identity: 42.41; identified by sequence similarity; putative. (387 aa)    
Predicted Functional Partners:
AF_2415
Acyl carrier protein synthase (acaA-2); Similar to PID:1197357 percent identity: 58.72; identified by sequence similarity; putative; Belongs to the thiolase-like superfamily. UPF0219 family.
 
 0.992
AF_0435
enoyl-CoA hydratase (fad-1); Similar to PID:755067 percent identity: 47.64; identified by sequence similarity; putative; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.967
AF_1190
3-hydroxyacyl-CoA dehydrogenase (hbd-7); Similar to PID:1055222 SP:P52041 percent identity: 46.45; identified by sequence similarity; putative.
  
 0.967
AF_1340
Citrate synthase (citZ); Similar to GB:U05257 SP:P39120 PID:487433 PID:2293267 GB:AL009126 percent identity: 50.27; identified by sequence similarity; putative.
  
 0.957
AF_0033
Acyl carrier protein synthase (acaA-1); Similar to PID:1197357 percent identity: 28.62; identified by sequence similarity; putative.
 
 0.935
leuA
2-isopropylmalate synthase (leuA-2); Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate).
  
 
 0.933
AF_0197
acetyl-CoA synthetase (acs-1); Similar to SP:P27550 PID:396404 PID:148105 GB:U00096 PID:1790505 percent identity: 27.14; identified by sequence similarity; putative.
  
 
 0.926
AF_0434
3-hydroxyacyl-CoA dehydrogenase (hbd-3); Similar to GB:M31799 PID:144733 percent identity: 40.73; identified by sequence similarity; putative.
  
 0.926
AF_0437
Conserved hypothetical protein; Similar to GB:L77117 PID:1592182 percent identity: 32.98; identified by sequence similarity; putative.
  
 
 0.903
AF_0019
Conserved hypothetical protein; Similar to PID:1163919 percent identity: 28.70; identified by sequence similarity; putative.
 
 
 0.902
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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