Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0448Signal-transducing histidine kinase, putative; Similar to PID:1001216 PID:1001267 percent identity: 26.09; identified by sequence similarity; putative. (771 aa)    
Predicted Functional Partners:
AF_0450
Signal-transducing histidine kinase; Similar to SP:P10955 GB:J03174 PID:152215 PID:49404 percent identity: 32.40; identified by sequence similarity; putative.
 
     0.846
AF_0449
Response regulator; Similar to GB:M59781 SP:P24072 PID:142682 GB:AL009126 percent identity: 38.14; identified by sequence similarity; putative.
   
 
 0.833
AF_0452
Conserved hypothetical protein; Similar to PID:1653695 percent identity: 29.42; identified by sequence similarity; putative.
 
     0.746
AF_0451
Predicted coding region AF_0451; Hypothetical protein; identified by GeneMark; putative.
       0.608
AF_0453
Predicted coding region AF_0453; Hypothetical protein; identified by GeneMark; putative.
       0.608
AF_0364
ATP-dependent protease La (lon); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Degrades polypeptides processively (By similarity).
 
 
 0.546
AF_0446
Conserved hypothetical protein; Similar to GP:1418667 percent identity: 41.54; identified by sequence similarity; putative.
       0.543
AF_0447
Predicted coding region AF_0447; Hypothetical protein; identified by GeneMark; putative.
       0.543
prs1
Ribose-phosphate pyrophosphokinase (prsA-1); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
   
 0.538
prs2
Ribose-phosphate pyrophosphokinase (prsA-2); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
   
 0.538
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.