Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0449Response regulator; Similar to GB:M59781 SP:P24072 PID:142682 GB:AL009126 percent identity: 38.14; identified by sequence similarity; putative. (125 aa)    
Predicted Functional Partners:
AF_0450
Signal-transducing histidine kinase; Similar to SP:P10955 GB:J03174 PID:152215 PID:49404 percent identity: 32.40; identified by sequence similarity; putative.
 
 
 
 0.913
AF_0448
Signal-transducing histidine kinase, putative; Similar to PID:1001216 PID:1001267 percent identity: 26.09; identified by sequence similarity; putative.
   
 
 0.833
AF_0208
Signal-transducing histidine kinase; Similar to PID:1001492 PID:1001594 percent identity: 27.88; identified by sequence similarity; putative.
 
 
 
 0.715
AF_1043
Predicted coding region AF_1043; Hypothetical protein; identified by GeneMark; putative.
   
 
 0.698
AF_1515
Signal-transducing histidine kinase; Similar to SP:P45670 PID:599601 percent identity: 24.05; identified by sequence similarity; putative.
 
 
 
 0.682
AF_2109
Signal-transducing histidine kinase; Similar to GB:M29450 SP:P16497 GB:M31067 PID:143333 PID:143631 percent identity: 26.96; identified by sequence similarity; putative.
 
 
 
 0.668
AF_0021
Signal-transducing histidine kinase; Similar to PID:950652 percent identity: 26.11; identified by sequence similarity; putative.
 
 
 
 0.658
AF_1639
Signal-transducing histidine kinase; Similar to SP:P10955 GB:J03174 PID:152215 PID:49404 percent identity: 29.91; identified by sequence similarity; putative.
 
 
 
 0.656
AF_1040
Chemotaxis histidine kinase (cheA); Similar to PID:940147 SP:Q56310 percent identity: 41.92; identified by sequence similarity; putative.
  
  
 0.652
AF_1184
Signal-transducing histidine kinase; Similar to SP:P10955 GB:J03174 PID:152215 PID:49404 percent identity: 29.81; identified by sequence similarity; putative.
 
 
 
 0.651
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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