Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AF_0460Conserved hypothetical protein; Similar to GB:L77117 PID:1591855 percent identity: 30.60; identified by sequence similarity; putative; Belongs to the UPF0216 family. (134 aa)    
Predicted Functional Partners:
AF_0461
Conserved hypothetical protein; Similar to GB:L77117 SP:Q59045 PID:1592233 percent identity: 39.83; identified by sequence similarity; putative.
       0.787
AF_0462
Conserved hypothetical transmembrane protein; Similar to GB:L77117 SP:Q57882 PID:1591144 percent identity: 33.08; identified by sequence similarity; putative.
       0.773
glnA
Glutamine synthetase (glnA); Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Beta-glutamate is a much poorer substrate than alpha-glutamate; Belongs to the glutamine synthetase family.
       0.624
AF_0226
NADH oxidase (noxC); Similar to GB:X60110 GB:S55441 PID:48247 PID:265804 percent identity: 38.36; identified by sequence similarity; putative.
       0.618
trm1
N2,N2-dimethylguanosine tRNA methyltransferase (trm1); Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
       0.516
atpD
H+-transporting ATP synthase, subunit D (atpD); Produces ATP from ADP in the presence of a proton gradient across the membrane.
       0.516
AF_1787
Conserved hypothetical protein; Similar to GB:L77117 PID:1591790 percent identity: 34.42; identified by sequence similarity; putative.
       0.516
flpA
Fibrillarin (fib); Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
       0.516
AF_2088
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58105 PID:1591409 percent identity: 38.19; identified by sequence similarity; putative.
       0.516
atpF
H+-transporting ATP synthase, subunit F (atpF); Produces ATP from ADP in the presence of a proton gradient across the membrane.
       0.476
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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