STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0464Bacteriochlorophyll synthase, 43 kDa subunit (chlP-1); Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. Is not active with NADPH as an electron donor. Is not able to reduce the prenyl group of respiratory quinones; Belong [...] (410 aa)    
Predicted Functional Partners:
AF_0404
4-hydroxybenzoate octaprenyltransferase, putative; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
 
 
 0.964
carS
Conserved hypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. Can use CTP or dCTP, but not ATP, GTP or TTP; Belongs to the CDP-archaeol synthase family.
  
  
 0.920
AF_0286
Electron transfer flavoprotein, subunit beta (etfB); Similar to GP:1903329 percent identity: 38.80; identified by sequence similarity; putative.
  
 
 0.840
AF_0287
Electron transfer flavoprotein, subunit alpha (etfA); Similar to PID:596026 SP:P53571 percent identity: 39.75; identified by sequence similarity; putative.
  
 
 0.778
AF_1445
Conserved hypothetical protein; Similar to GP:1524204 percent identity: 26.18; identified by sequence similarity; putative.
 
  
 0.669
AF_1648
Bacteriochlorophyll synthase, 33 kDa subunit; Similar to PID:1001103 PID:1001139 percent identity: 27.92; identified by sequence similarity; putative.
 
  
 0.443
AF_1551
Octaprenyl-diphosphate synthase (ispB); Similar to GB:L42023 SP:P44916 PID:1005963 PID:1220984 PID:1205128 percent identity: 33.20; identified by sequence similarity; putative; Belongs to the FPP/GGPP synthase family.
 
 
 0.441
AF_1444
Predicted coding region AF_1444; Hypothetical protein; identified by GeneMark; putative.
 
  
 0.415
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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