| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AF_0465 | AF_2430 | AF_0465 | AF_2430 | DNA gyrase, subunit A (gyrA); Similar to GB:D26185 SP:P05653 GB:X02369 PID:40019 PID:467397 percent identity: 48.45; identified by sequence similarity; putative. | lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative. | 0.718 |
| AF_0465 | gyrB | AF_0465 | AF_0530 | DNA gyrase, subunit A (gyrA); Similar to GB:D26185 SP:P05653 GB:X02369 PID:40019 PID:467397 percent identity: 48.45; identified by sequence similarity; putative. | DNA gyrase, subunit B (gyrB); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.999 |
| AF_0465 | hisS | AF_0465 | AF_1642 | DNA gyrase, subunit A (gyrA); Similar to GB:D26185 SP:P05653 GB:X02369 PID:40019 PID:467397 percent identity: 48.45; identified by sequence similarity; putative. | histidyl-tRNA synthetase (hisS); Similar to GB:L77117 SP:Q58406 PID:1591660 percent identity: 45.97; identified by sequence similarity; putative; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.822 |
| AF_0465 | ileS | AF_0465 | AF_0633 | DNA gyrase, subunit A (gyrA); Similar to GB:D26185 SP:P05653 GB:X02369 PID:40019 PID:467397 percent identity: 48.45; identified by sequence similarity; putative. | isoleucyl-tRNA synthetase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.829 |
| AF_0465 | metG | AF_0465 | AF_1453 | DNA gyrase, subunit A (gyrA); Similar to GB:D26185 SP:P05653 GB:X02369 PID:40019 PID:467397 percent identity: 48.45; identified by sequence similarity; putative. | methionyl-tRNA synthetase (metS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.846 |
| AF_0465 | nusA | AF_0465 | AF_1891 | DNA gyrase, subunit A (gyrA); Similar to GB:D26185 SP:P05653 GB:X02369 PID:40019 PID:467397 percent identity: 48.45; identified by sequence similarity; putative. | Transcription termination-antitermination factor NusA, putative; Participates in transcription termination. Belongs to the NusA family. | 0.726 |
| AF_0465 | rpl11 | AF_0465 | AF_0538 | DNA gyrase, subunit A (gyrA); Similar to GB:D26185 SP:P05653 GB:X02369 PID:40019 PID:467397 percent identity: 48.45; identified by sequence similarity; putative. | LSU ribosomal protein L11P (rpl11P); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. | 0.734 |
| AF_0465 | rpoD | AF_0465 | AF_2282 | DNA gyrase, subunit A (gyrA); Similar to GB:D26185 SP:P05653 GB:X02369 PID:40019 PID:467397 percent identity: 48.45; identified by sequence similarity; putative. | DNA-directed RNA polymerase, subunit D (rpoD); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.716 |
| AF_0465 | rps9 | AF_0465 | AF_1129 | DNA gyrase, subunit A (gyrA); Similar to GB:D26185 SP:P05653 GB:X02369 PID:40019 PID:467397 percent identity: 48.45; identified by sequence similarity; putative. | SSU ribosomal protein S9P (rps9P); Similar to SP:P05763 GB:M76567 PID:148778 percent identity: 59.54; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS9 family. | 0.761 |
| AF_0465 | serS | AF_0465 | AF_2035 | DNA gyrase, subunit A (gyrA); Similar to GB:D26185 SP:P05653 GB:X02369 PID:40019 PID:467397 percent identity: 48.45; identified by sequence similarity; putative. | seryl-tRNA synthetase (serS); Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.720 |
| AF_2430 | AF_0465 | AF_2430 | AF_0465 | lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative. | DNA gyrase, subunit A (gyrA); Similar to GB:D26185 SP:P05653 GB:X02369 PID:40019 PID:467397 percent identity: 48.45; identified by sequence similarity; putative. | 0.718 |
| AF_2430 | gyrB | AF_2430 | AF_0530 | lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative. | DNA gyrase, subunit B (gyrB); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.587 |
| AF_2430 | hisS | AF_2430 | AF_1642 | lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative. | histidyl-tRNA synthetase (hisS); Similar to GB:L77117 SP:Q58406 PID:1591660 percent identity: 45.97; identified by sequence similarity; putative; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.672 |
| AF_2430 | nusA | AF_2430 | AF_1891 | lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative. | Transcription termination-antitermination factor NusA, putative; Participates in transcription termination. Belongs to the NusA family. | 0.499 |
| gyrB | AF_0465 | AF_0530 | AF_0465 | DNA gyrase, subunit B (gyrB); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA gyrase, subunit A (gyrA); Similar to GB:D26185 SP:P05653 GB:X02369 PID:40019 PID:467397 percent identity: 48.45; identified by sequence similarity; putative. | 0.999 |
| gyrB | AF_2430 | AF_0530 | AF_2430 | DNA gyrase, subunit B (gyrB); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative. | 0.587 |
| gyrB | ileS | AF_0530 | AF_0633 | DNA gyrase, subunit B (gyrB); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | isoleucyl-tRNA synthetase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.780 |
| gyrB | metG | AF_0530 | AF_1453 | DNA gyrase, subunit B (gyrB); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | methionyl-tRNA synthetase (metS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.641 |
| gyrB | rpl11 | AF_0530 | AF_0538 | DNA gyrase, subunit B (gyrB); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | LSU ribosomal protein L11P (rpl11P); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. | 0.753 |
| gyrB | rpoD | AF_0530 | AF_2282 | DNA gyrase, subunit B (gyrB); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA-directed RNA polymerase, subunit D (rpoD); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.461 |
STRING v12.5 is now available!
