Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
copACation-transporting ATPase, P-type (pacS); Probably involved in copper and silver export. (804 aa)    
Predicted Functional Partners:
copZ
Mercuric transport protein periplasmic component (merP); Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) directly to the transmembrane transport sites of copper-exporting P-type ATPase A (CopA). Probably has a redox function due to the presence of a 2Fe-2S cluster and could reduce Cu(2+) to Cu(+).
     
0.973
AF_0474
Transcriptional regulatory protein, AsnC family; Similar to SP:P42180 percent identity: 36.84; identified by sequence similarity; putative.
     
 0.943
AF_1448
Transcriptional regulatory protein, AsnC family; Similar to GB:L77117 SP:Q58133 PID:1591440 percent identity: 30.58; identified by sequence similarity; putative.
     
 0.877
AF_1743
Transcriptional regulatory protein, AsnC family; Similar to SP:P42180 percent identity: 34.91; identified by sequence similarity; putative.
     
 0.877
AF_0412
Predicted coding region AF_0412; Hypothetical protein; identified by GeneMark; putative.
      
 0.802
AF_1188
Conserved hypothetical protein; Similar to GP:1788023 percent identity: 29.56; identified by sequence similarity; putative.
      
 0.802
AF_2144
Thioredoxin (trx-4); Similar to SP:P37395 percent identity: 48.94; identified by sequence similarity; putative.
     
 0.645
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
     
 0.625
AF_1284
Thioredoxin (trx-3); Similar to SP:P00275 percent identity: 52.94; identified by sequence similarity; putative.
 
   
 0.565
AF_1420
Membrane protein; Similar to GB:L77117 SP:Q58237 PID:1591514 percent identity: 51.83; identified by sequence similarity; putative.
     
 0.539
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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