Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AF_0477AAA superfamily ATPase; Similar to GB:D78275 SP:Q92524 PID:1526426 PID:2213932 percent identity: 34.97; identified by sequence similarity; putative; Belongs to the AAA ATPase family. (409 aa)    
Predicted Functional Partners:
AF_0478
ATP-binding protein PhnP (phnP); Similar to GB:D90227 SP:P16692 PID:147213 PID:216605 PID:536936 percent identity: 30.94; identified by sequence similarity; putative.
 
     0.931
rpl40e
LSU ribosomal protein L40E (rpl40E); Similar to GB:L77117 SP:P54058 PID:1591423 percent identity: 73.33; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.837
pan
26S protease regulatory subunit 4; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...]
 
0.812
AF_0479
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58250 PID:1591527 percent identity: 41.38; identified by sequence similarity; putative.
       0.803
AF_0866
Glycerol kinase (glpK); Similar to GB:M34393 SP:P18157 PID:142992 PID:2226137 GB:AL009126 percent identity: 33.83; identified by sequence similarity; putative; Belongs to the FGGY kinase family.
  
  0.802
AF_0130
Acetylpolyamine aminohydrolase (aphA); Probable deacetylase; Belongs to the histone deacetylase family.
   
 0.793
AF_0690
Predicted coding region AF_0690; Hypothetical protein; identified by GeneMark; putative.
   
 0.793
AF_1286
Acetoin utilization protein, putative; Similar to PID:1177686 percent identity: 35.06; identified by sequence similarity; putative.
   
 0.793
AF_2290
Acetylpolyamine aminohydrolase, putative; Similar to GB:D10463 PID:520593 percent identity: 33.33; identified by sequence similarity; putative.
   
 0.793
AF_2198
Conserved hypothetical protein; Similar to SP:Q10645 PID:1340100 percent identity: 23.28; identified by sequence similarity; putative.
 
 0.785
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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