Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0478ATP-binding protein PhnP (phnP); Similar to GB:D90227 SP:P16692 PID:147213 PID:216605 PID:536936 percent identity: 30.94; identified by sequence similarity; putative. (254 aa)    
Predicted Functional Partners:
AF_0477
AAA superfamily ATPase; Similar to GB:D78275 SP:Q92524 PID:1526426 PID:2213932 percent identity: 34.97; identified by sequence similarity; putative; Belongs to the AAA ATPase family.
 
     0.931
trpCD
Anthranilate synthase component II (trpD); Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway. The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
     
 0.830
AF_0479
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58250 PID:1591527 percent identity: 41.38; identified by sequence similarity; putative.
       0.807
ef1b
Translation elongation factor EF-1, subunit beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
       0.711
AF_0572
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57900 PID:1499252 percent identity: 34.36; identified by sequence similarity; putative.
       0.681
AF_0573
Predicted coding region AF_0573; Hypothetical protein; identified by GeneMark; putative.
       0.681
rnz
Conserved hypothetical protein; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
 
   
 0.645
AF_1801
Conserved hypothetical protein; Similar to GB:L77117 PID:1592115 percent identity: 35.16; identified by sequence similarity; putative.
       0.593
AF_0475
Conserved hypothetical protein; Similar to SP:P45946 PID:1217884 PID:1303777 GB:AL009126 percent identity: 60.06; identified by sequence similarity; putative.
       0.545
AF_0299
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58021 PID:1591313 percent identity: 41.11; identified by sequence similarity; putative.
       0.539
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.