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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0482mRNA 3'-end processing factor, putative; Similar to GB:L77117 SP:Q58633 PID:1591868 percent identity: 55.48; identified by sequence similarity; putative. (632 aa)    
Predicted Functional Partners:
psmB
Proteasome, subunit beta (psmB); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
     
 0.872
psmA
Proteasome, subunit alpha (psmA); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
   
 0.593
AF_1341
Thymidine phosphorylase (deoA-1); Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
 
     0.591
AF_2253
Molybdopterin-guanine dinucleotide biosynthesis protein B (mobB); Similar to GB:L77117 PID:1591964 percent identity: 40.00; identified by sequence similarity; putative.
       0.564
AF_0480
Fuculose-1-phosphate aldolase (fucA); Similar to GB:L77117 SP:Q58813 PID:1592067 percent identity: 31.84; identified by sequence similarity; putative.
       0.556
AF_0491
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58011 PID:1592297 percent identity: 57.33; identified by sequence similarity; putative; Belongs to the SDO1/SBDS family.
 
   
 0.538
AF_0116
Uroporphyrinogen III synthase (hemD); Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
       0.534
AF_1342
Thymidine phosphorylase (deoA-2); Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
 
     0.534
AF_0483
Conserved hypothetical protein; Similar to GB:L77117 PID:1500013 percent identity: 32.26; identified by sequence similarity; putative.
       0.523
rrp42
Conserved hypothetical protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.
     
 0.518
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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