| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AF_0491 | psmA | AF_0491 | AF_0490 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58011 PID:1592297 percent identity: 57.33; identified by sequence similarity; putative; Belongs to the SDO1/SBDS family. | Proteasome, subunit alpha (psmA); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.968 |
| AF_0491 | psmB | AF_0491 | AF_0481 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58011 PID:1592297 percent identity: 57.33; identified by sequence similarity; putative; Belongs to the SDO1/SBDS family. | Proteasome, subunit beta (psmB); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.601 |
| AF_0491 | rnp2 | AF_0491 | AF_0489 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58011 PID:1592297 percent identity: 57.33; identified by sequence similarity; putative; Belongs to the SDO1/SBDS family. | Conserved hypothetical protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family. | 0.912 |
| AF_0491 | rpl37ae | AF_0491 | AF_0057 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58011 PID:1592297 percent identity: 57.33; identified by sequence similarity; putative; Belongs to the SDO1/SBDS family. | LSU ribosomal protein L37AE (rpl37AE); Binds to the 23S rRNA. | 0.985 |
| AF_0491 | rrp4 | AF_0491 | AF_0492 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58011 PID:1592297 percent identity: 57.33; identified by sequence similarity; putative; Belongs to the SDO1/SBDS family. | Conserved hypothetical protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome (Probable); Belongs to the RRP4 family. | 0.940 |
| AF_0491 | rrp41 | AF_0491 | AF_0493 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58011 PID:1592297 percent identity: 57.33; identified by sequence similarity; putative; Belongs to the SDO1/SBDS family. | Ribonuclease PH (rph); Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails (Probable). | 0.950 |
| AF_0491 | rrp42 | AF_0491 | AF_0494 | Conserved hypothetical protein; Similar to GB:L77117 SP:Q58011 PID:1592297 percent identity: 57.33; identified by sequence similarity; putative; Belongs to the SDO1/SBDS family. | Conserved hypothetical protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. | 0.949 |
| AF_0866 | AF_2198 | AF_0866 | AF_2198 | Glycerol kinase (glpK); Similar to GB:M34393 SP:P18157 PID:142992 PID:2226137 GB:AL009126 percent identity: 33.83; identified by sequence similarity; putative; Belongs to the FGGY kinase family. | Conserved hypothetical protein; Similar to SP:Q10645 PID:1340100 percent identity: 23.28; identified by sequence similarity; putative. | 0.969 |
| AF_0866 | pan | AF_0866 | AF_1976 | Glycerol kinase (glpK); Similar to GB:M34393 SP:P18157 PID:142992 PID:2226137 GB:AL009126 percent identity: 33.83; identified by sequence similarity; putative; Belongs to the FGGY kinase family. | 26S protease regulatory subunit 4; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | 0.971 |
| AF_0866 | psmA | AF_0866 | AF_0490 | Glycerol kinase (glpK); Similar to GB:M34393 SP:P18157 PID:142992 PID:2226137 GB:AL009126 percent identity: 33.83; identified by sequence similarity; putative; Belongs to the FGGY kinase family. | Proteasome, subunit alpha (psmA); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.923 |
| AF_0866 | psmB | AF_0866 | AF_0481 | Glycerol kinase (glpK); Similar to GB:M34393 SP:P18157 PID:142992 PID:2226137 GB:AL009126 percent identity: 33.83; identified by sequence similarity; putative; Belongs to the FGGY kinase family. | Proteasome, subunit beta (psmB); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.923 |
| AF_2198 | AF_0866 | AF_2198 | AF_0866 | Conserved hypothetical protein; Similar to SP:Q10645 PID:1340100 percent identity: 23.28; identified by sequence similarity; putative. | Glycerol kinase (glpK); Similar to GB:M34393 SP:P18157 PID:142992 PID:2226137 GB:AL009126 percent identity: 33.83; identified by sequence similarity; putative; Belongs to the FGGY kinase family. | 0.969 |
| AF_2198 | pan | AF_2198 | AF_1976 | Conserved hypothetical protein; Similar to SP:Q10645 PID:1340100 percent identity: 23.28; identified by sequence similarity; putative. | 26S protease regulatory subunit 4; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | 0.981 |
| AF_2198 | psmA | AF_2198 | AF_0490 | Conserved hypothetical protein; Similar to SP:Q10645 PID:1340100 percent identity: 23.28; identified by sequence similarity; putative. | Proteasome, subunit alpha (psmA); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.919 |
| AF_2198 | psmB | AF_2198 | AF_0481 | Conserved hypothetical protein; Similar to SP:Q10645 PID:1340100 percent identity: 23.28; identified by sequence similarity; putative. | Proteasome, subunit beta (psmB); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.919 |
| AF_2198 | rpl37ae | AF_2198 | AF_0057 | Conserved hypothetical protein; Similar to SP:Q10645 PID:1340100 percent identity: 23.28; identified by sequence similarity; putative. | LSU ribosomal protein L37AE (rpl37AE); Binds to the 23S rRNA. | 0.704 |
| pan | AF_0866 | AF_1976 | AF_0866 | 26S protease regulatory subunit 4; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | Glycerol kinase (glpK); Similar to GB:M34393 SP:P18157 PID:142992 PID:2226137 GB:AL009126 percent identity: 33.83; identified by sequence similarity; putative; Belongs to the FGGY kinase family. | 0.971 |
| pan | AF_2198 | AF_1976 | AF_2198 | 26S protease regulatory subunit 4; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | Conserved hypothetical protein; Similar to SP:Q10645 PID:1340100 percent identity: 23.28; identified by sequence similarity; putative. | 0.981 |
| pan | psmA | AF_1976 | AF_0490 | 26S protease regulatory subunit 4; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | Proteasome, subunit alpha (psmA); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.996 |
| pan | psmB | AF_1976 | AF_0481 | 26S protease regulatory subunit 4; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | Proteasome, subunit beta (psmB); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.996 |
