Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
AF_0491Conserved hypothetical protein; Similar to GB:L77117 SP:Q58011 PID:1592297 percent identity: 57.33; identified by sequence similarity; putative; Belongs to the SDO1/SBDS family. (234 aa)    
Predicted Functional Partners:
rpl37ae
LSU ribosomal protein L37AE (rpl37AE); Binds to the 23S rRNA.
  
   0.985
psmA
Proteasome, subunit alpha (psmA); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
  
 0.968
fusA
Translation elongation factor EF-2 (fus); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor G [...]
 
 
 0.955
rrp41
Ribonuclease PH (rph); Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails (Probable).
 
  
 0.950
rrp42
Conserved hypothetical protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.
 
  
 0.949
rpl15e
LSU ribosomal protein L15E (rpl15E); Similar to GB:L77117 SP:P54060 PID:1591645 percent identity: 70.31; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL15 family.
 
 
 0.941
rrp4
Conserved hypothetical protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome (Probable); Belongs to the RRP4 family.
 
    0.940
rps19e
SSU ribosomal protein S19E (rps19E); May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
  
 
 0.931
eif6
Conserved hypothetical protein; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
 
 
 0.925
rps8e
SSU ribosomal protein S8E (rps8E); Similar to GB:L77117 SP:P54055 PID:1591387 percent identity: 61.60; identified by sequence similarity; putative.
  
 
 0.923
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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