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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0491Conserved hypothetical protein; Similar to GB:L77117 SP:Q58011 PID:1592297 percent identity: 57.33; identified by sequence similarity; putative; Belongs to the SDO1/SBDS family. (234 aa)    
Predicted Functional Partners:
rpl37ae
LSU ribosomal protein L37AE (rpl37AE); Binds to the 23S rRNA.
  
   0.978
fusA
Translation elongation factor EF-2 (fus); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor G [...]
 
 
 0.959
rrp41
Ribonuclease PH (rph); Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails (Probable).
 
  
 0.949
psmA
Proteasome, subunit alpha (psmA); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
    0.946
rps19e
SSU ribosomal protein S19E (rps19E); May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
  
 
 0.940
rps8e
SSU ribosomal protein S8E (rps8E); Similar to GB:L77117 SP:P54055 PID:1591387 percent identity: 61.60; identified by sequence similarity; putative.
  
 
 0.929
rpl15e
LSU ribosomal protein L15E (rpl15E); Similar to GB:L77117 SP:P54060 PID:1591645 percent identity: 70.31; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL15 family.
 
 
 0.928
rpl4
LSU ribosomal protein L4P (rpl4P); One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
 
   0.921
rpl7ae
LSU ribosomal protein L7AE (rpl7AE); Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
  
 
 0.915
rps17e
SSU ribosomal protein S17E (rps17E); Similar to PIR:S63968 percent identity: 52.63; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS17 family.
  
 
 0.908
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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