close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmeAMolybdopterin oxidoreductase, iron-sulfur binding subunit; Has menaquinol-oxidizing activity. HmeA, HmeB and HmeE subunits may together catalyze electron transfer from menaquinol to cytochrome c. (269 aa)    
Predicted Functional Partners:
hmeB
Molybdopterin oxidoreductase, membrane subunit; Has menaquinol-oxidizing activity. HmeB subunit may function as a menaquinol-oxidizing site. HmeA, HmeB and HmeE subunits may together catalyze electron transfer from menaquinol to cytochrome c.
 
 
 0.986
AF_0174
Molybdopterin oxidoreductase, membrane subunit; Similar to SP:P31077 GB:X65042 PID:48528 percent identity: 26.03; identified by sequence similarity; putative.
 
 
 0.955
ttrA
Molybdopterin oxidoreductase, molybdopterin binding subunit, putative; Part of a membrane-bound tetrathionate reductase that catalyzes the reduction of tetrathionate to thiosulfate. TtrA is the catalytic subunit (By similarity).
 
 
 0.939
hmeD
Heterodisulfide reductase, subunit D, putative; Has menaquinol-oxidizing activity. HmeC and HmeD subunits may together mediate electron transfer from menaquinol to an unidentified electron acceptor on the cytoplasmic side of the membrane.
 
  
 0.920
AF_0176
Molybdopterin oxidoreductase, molybdopterin binding subunit; Similar to SP:P09152 GB:X16181 GB:X01164 GB:X15996 PID:146926 percent identity: 32.57; identified by sequence similarity; putative.
 
 
 0.902
AF_2384
Molybdopterin oxidoreductase, molybdopterin binding subunit; Similar to SP:P31075 GB:X65042 PID:48526 percent identity: 34.56; identified by sequence similarity; putative.
 
 0.902
hmeC
Nitrate reductase, gamma subunit, putative; Has menaquinol-oxidizing activity. HmeC and HmeD subunits may together mediate electron transfer from menaquinol to an unidentified electron acceptor on the cytoplasmic side of the membrane.
 
  
 0.886
AF_1379
Quinone-reactive Ni/Fe-hydrogenase B-type cytochrome subunit (hydC); Similar to SP:P31875 PID:48518 percent identity: 29.03; identified by sequence similarity; putative.
  
 
 0.878
AF_1203
Molybdopterin oxidoreductase, molybdopterin binding subunit; Similar to SP:P31075 GB:X65042 PID:48526 percent identity: 30.05; identified by sequence similarity; putative.
 
 0.877
hmeE
Predicted coding region AF_0503; Has menaquinol-oxidizing activity. HmeA, HmeB and HmeE subunits may together catalyze electron transfer from menaquinol to cytochrome c.
 
  
 0.876
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.