close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmeDHeterodisulfide reductase, subunit D, putative; Has menaquinol-oxidizing activity. HmeC and HmeD subunits may together mediate electron transfer from menaquinol to an unidentified electron acceptor on the cytoplasmic side of the membrane. (555 aa)    
Predicted Functional Partners:
hmeC
Nitrate reductase, gamma subunit, putative; Has menaquinol-oxidizing activity. HmeC and HmeD subunits may together mediate electron transfer from menaquinol to an unidentified electron acceptor on the cytoplasmic side of the membrane.
 
 
 0.982
hmeE
Predicted coding region AF_0503; Has menaquinol-oxidizing activity. HmeA, HmeB and HmeE subunits may together catalyze electron transfer from menaquinol to cytochrome c.
 
    0.940
hmeB
Molybdopterin oxidoreductase, membrane subunit; Has menaquinol-oxidizing activity. HmeB subunit may function as a menaquinol-oxidizing site. HmeA, HmeB and HmeE subunits may together catalyze electron transfer from menaquinol to cytochrome c.
 
   
 0.924
dsrB
Sulfite reductase, subunit beta (dsrB); Catalyzes the reduction of sulfite to sulfide. This is the terminal oxidation reaction in sulfate respiration.
 
 
 0.920
hmeA
Molybdopterin oxidoreductase, iron-sulfur binding subunit; Has menaquinol-oxidizing activity. HmeA, HmeB and HmeE subunits may together catalyze electron transfer from menaquinol to cytochrome c.
 
  
 0.920
dsrA
Sulfite reductase, subunit alpha (dsrA); Catalyzes the reduction of sulfite to sulfide. This is the terminal oxidation reaction in sulfate respiration.
 
 
 0.917
AF_2228
Sulfite reductase, desulfoviridin-type subunit gamma (dsvC); Similar to GB:L42023 SP:P45184 PID:1007407 PID:1221507 PID:1205607 percent identity: 41.28; identified by sequence similarity; putative.
 
 
 
 0.826
AF_0545
Predicted coding region AF_0545; Hypothetical protein; identified by GeneMark; putative.
 
 
 0.802
AF_0546
Nitrate reductase, gamma subunit (narI); Similar to GB:Z26255 percent identity: 30.14; identified by sequence similarity; putative.
 
 
 0.737
AF_0811
Conserved hypothetical protein; Similar to GP:1657506 percent identity: 32.60; identified by sequence similarity; putative.
  
 
 0.702
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: medium (52%) [HD]