Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AF_0524Predicted coding region AF_0524; Hypothetical protein; identified by GeneMark; putative. (225 aa)    
Predicted Functional Partners:
eif2a
Translation initiation factor eIF-2, subunit alpha (eif2A); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family.
 
     0.807
AF_1245
Na+/H+ antiporter (napA-2); Similar to SP:P26235 PID:148316 percent identity: 28.41; identified by sequence similarity; putative.
  
    0.802
AF_2276
Conserved hypothetical protein; Similar to GB:L77117 PID:1591555 percent identity: 39.31; identified by sequence similarity; putative.
   
    0.787
AF_0525
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58607 PID:1591839 percent identity: 46.86; identified by sequence similarity; putative.
       0.773
nop10
Conserved hypothetical protein; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
       0.773
pyrK
Cytochrome-c3 hydrogenase, subunit gamma; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
       0.658
AF_1183
Predicted coding region AF_1183; Hypothetical protein; identified by GeneMark; putative.
       0.608
AF_1528
Conserved hypothetical protein; Similar to GB:L77117 PID:1499710 percent identity: 23.20; identified by sequence similarity; putative.
   
    0.604
mptA
Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
  
    0.543
AF_0529
Predicted coding region AF_0529; Hypothetical protein; identified by GeneMark; putative.
       0.439
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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