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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0525Conserved hypothetical protein; Similar to GB:L77117 SP:Q58607 PID:1591839 percent identity: 46.86; identified by sequence similarity; putative. (259 aa)    
Predicted Functional Partners:
eif2a
Translation initiation factor eIF-2, subunit alpha (eif2A); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family.
 
    0.892
nop10
Conserved hypothetical protein; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
       0.847
rpl44e
LSU ribosomal protein L44E (rpl44E); Binds to the 23S rRNA.
 
     0.781
AF_0524
Predicted coding region AF_0524; Hypothetical protein; identified by GeneMark; putative.
       0.773
pyrK
Cytochrome-c3 hydrogenase, subunit gamma; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
 
     0.704
polC
Conserved hypothetical protein; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
  
     0.646
AF_1012
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57970 PID:1591255 percent identity: 38.49; identified by sequence similarity; putative.
  
     0.632
eif5a
Translation initiation factor eIF-5A (eif5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
   
 0.629
AF_0735
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58387 PID:1591640 percent identity: 36.87; identified by sequence similarity; putative.
  
     0.628
AF_2198
Conserved hypothetical protein; Similar to SP:Q10645 PID:1340100 percent identity: 23.28; identified by sequence similarity; putative.
  
     0.627
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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