| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AF_0465 | AF_2430 | AF_0465 | AF_2430 | DNA gyrase, subunit A (gyrA); Similar to GB:D26185 SP:P05653 GB:X02369 PID:40019 PID:467397 percent identity: 48.45; identified by sequence similarity; putative. | lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative. | 0.913 |
| AF_0465 | fusA | AF_0465 | AF_1894 | DNA gyrase, subunit A (gyrA); Similar to GB:D26185 SP:P05653 GB:X02369 PID:40019 PID:467397 percent identity: 48.45; identified by sequence similarity; putative. | Translation elongation factor EF-2 (fus); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor G [...] | 0.642 |
| AF_0465 | gyrB | AF_0465 | AF_0530 | DNA gyrase, subunit A (gyrA); Similar to GB:D26185 SP:P05653 GB:X02369 PID:40019 PID:467397 percent identity: 48.45; identified by sequence similarity; putative. | DNA gyrase, subunit B (gyrB); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.999 |
| AF_0465 | top6A | AF_0465 | AF_0940 | DNA gyrase, subunit A (gyrA); Similar to GB:D26185 SP:P05653 GB:X02369 PID:40019 PID:467397 percent identity: 48.45; identified by sequence similarity; putative. | DNA topoisomerase VI, subunit A (top6A); Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. | 0.669 |
| AF_0465 | top6B | AF_0465 | AF_0652 | DNA gyrase, subunit A (gyrA); Similar to GB:D26185 SP:P05653 GB:X02369 PID:40019 PID:467397 percent identity: 48.45; identified by sequence similarity; putative. | DNA topoisomerase VI, subunit B (top6B); Relaxes both positive and negative superturns and exhibits a strong decatenase activity. | 0.827 |
| AF_2350 | fusA | AF_2350 | AF_1894 | ATP-dependent RNA helicase HepA, putative; Similar to SP:P54509 PID:1303889 GB:AL009126 percent identity: 31.49; identified by sequence similarity; putative. | Translation elongation factor EF-2 (fus); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor G [...] | 0.709 |
| AF_2350 | gyrB | AF_2350 | AF_0530 | ATP-dependent RNA helicase HepA, putative; Similar to SP:P54509 PID:1303889 GB:AL009126 percent identity: 31.49; identified by sequence similarity; putative. | DNA gyrase, subunit B (gyrB); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.845 |
| AF_2350 | smc | AF_2350 | AF_1558 | ATP-dependent RNA helicase HepA, putative; Similar to SP:P54509 PID:1303889 GB:AL009126 percent identity: 31.49; identified by sequence similarity; putative. | Chromosome segregation protein (smc1); Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.738 |
| AF_2350 | top6A | AF_2350 | AF_0940 | ATP-dependent RNA helicase HepA, putative; Similar to SP:P54509 PID:1303889 GB:AL009126 percent identity: 31.49; identified by sequence similarity; putative. | DNA topoisomerase VI, subunit A (top6A); Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. | 0.422 |
| AF_2350 | truB | AF_2350 | AF_0238 | ATP-dependent RNA helicase HepA, putative; Similar to SP:P54509 PID:1303889 GB:AL009126 percent identity: 31.49; identified by sequence similarity; putative. | Centromere/microtubule-binding protein (cbf5); Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.441 |
| AF_2430 | AF_0465 | AF_2430 | AF_0465 | lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative. | DNA gyrase, subunit A (gyrA); Similar to GB:D26185 SP:P05653 GB:X02369 PID:40019 PID:467397 percent identity: 48.45; identified by sequence similarity; putative. | 0.913 |
| AF_2430 | gyrB | AF_2430 | AF_0530 | lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative. | DNA gyrase, subunit B (gyrB); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.808 |
| fusA | AF_0465 | AF_1894 | AF_0465 | Translation elongation factor EF-2 (fus); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor G [...] | DNA gyrase, subunit A (gyrA); Similar to GB:D26185 SP:P05653 GB:X02369 PID:40019 PID:467397 percent identity: 48.45; identified by sequence similarity; putative. | 0.642 |
| fusA | AF_2350 | AF_1894 | AF_2350 | Translation elongation factor EF-2 (fus); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor G [...] | ATP-dependent RNA helicase HepA, putative; Similar to SP:P54509 PID:1303889 GB:AL009126 percent identity: 31.49; identified by sequence similarity; putative. | 0.709 |
| fusA | gyrB | AF_1894 | AF_0530 | Translation elongation factor EF-2 (fus); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor G [...] | DNA gyrase, subunit B (gyrB); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.836 |
| fusA | rgy | AF_1894 | AF_1024 | Translation elongation factor EF-2 (fus); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor G [...] | Reverse gyrase (top-RG); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family. | 0.732 |
| fusA | truB | AF_1894 | AF_0238 | Translation elongation factor EF-2 (fus); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor G [...] | Centromere/microtubule-binding protein (cbf5); Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.466 |
| gyrB | AF_0465 | AF_0530 | AF_0465 | DNA gyrase, subunit B (gyrB); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA gyrase, subunit A (gyrA); Similar to GB:D26185 SP:P05653 GB:X02369 PID:40019 PID:467397 percent identity: 48.45; identified by sequence similarity; putative. | 0.999 |
| gyrB | AF_2350 | AF_0530 | AF_2350 | DNA gyrase, subunit B (gyrB); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | ATP-dependent RNA helicase HepA, putative; Similar to SP:P54509 PID:1303889 GB:AL009126 percent identity: 31.49; identified by sequence similarity; putative. | 0.845 |
| gyrB | AF_2430 | AF_0530 | AF_2430 | DNA gyrase, subunit B (gyrB); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | lacZ expression regulatory protein (icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative. | 0.808 |
