Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0532mRNA 3'-end processing factor, putative; Similar to GB:L77117 SP:Q60355 PID:1590845 percent identity: 39.36; identified by sequence similarity; putative. (407 aa)    
Predicted Functional Partners:
AF_2049
Conserved hypothetical protein; Similar to GB:L77117 PID:1591954 percent identity: 31.36; identified by sequence similarity; putative.
   
 0.905
AF_1822
Serine/threonine phosphatase (ppa); Similar to PID:1016001 percent identity: 31.94; identified by sequence similarity; putative.
 
 0.819
AF_1953
Predicted coding region AF_1953; Hypothetical protein; identified by GeneMark; putative.
  
 0.782
AF_1388
DNA helicase, putative; Similar to GB:L77117 SP:Q57568 PID:1590880 percent identity: 46.83; identified by sequence similarity; putative.
   
 0.781
AF_1960
DNA helicase, putative; Similar to GB:L77117 SP:Q57568 PID:1590880 percent identity: 32.71; identified by sequence similarity; putative.
   
 0.781
AF_0533
Conserved hypothetical protein; Similar to GB:L77117 PID:1591788 percent identity: 36.61; identified by sequence similarity; putative.
       0.775
mre11
DNA repair protein RAD32 (rad32); Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family.
  
 0.771
AF_2117
3-methyladenine DNA glycosylase (alkA); Similar to GB:D14465 SP:P37878 PID:436209 GB:AL009126 percent identity: 30.05; identified by sequence similarity; putative.
  
  
 0.670
rpoP
Predicted coding region AF_0056; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.
   
 0.643
AF_1970
TPR domain-containing protein; Similar to GB:L04733 SP:Q07866 PID:307085 percent identity: 29.03; identified by sequence similarity; putative.
  
 0.633
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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