Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0533Conserved hypothetical protein; Similar to GB:L77117 PID:1591788 percent identity: 36.61; identified by sequence similarity; putative. (206 aa)    
Predicted Functional Partners:
AF_0532
mRNA 3'-end processing factor, putative; Similar to GB:L77117 SP:Q60355 PID:1590845 percent identity: 39.36; identified by sequence similarity; putative.
       0.775
AF_2001
Conserved hypothetical protein; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily.
 
     0.661
AF_0531
Molybdenum cofactor biosynthesis protein (moeB); Similar to PID:1653525 percent identity: 43.96; identified by sequence similarity; putative.
       0.574
AF_0626
Conserved hypothetical protein; Similar to PID:1653802 percent identity: 34.25; identified by sequence similarity; putative.
       0.564
gyrB
DNA gyrase, subunit B (gyrB); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.538
rps8e
SSU ribosomal protein S8E (rps8E); Similar to GB:L77117 SP:P54055 PID:1591387 percent identity: 61.60; identified by sequence similarity; putative.
 
     0.438
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.