Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0539Conserved hypothetical protein; Similar to PID:662338 percent identity: 34.10; identified by sequence similarity; putative. (231 aa)    
Predicted Functional Partners:
AF_1822
Serine/threonine phosphatase (ppa); Similar to PID:1016001 percent identity: 31.94; identified by sequence similarity; putative.
  
 0.896
AF_1388
DNA helicase, putative; Similar to GB:L77117 SP:Q57568 PID:1590880 percent identity: 46.83; identified by sequence similarity; putative.
   
 0.787
AF_1953
Predicted coding region AF_1953; Hypothetical protein; identified by GeneMark; putative.
   
 0.787
AF_1960
DNA helicase, putative; Similar to GB:L77117 SP:Q57568 PID:1590880 percent identity: 32.71; identified by sequence similarity; putative.
   
 0.787
AF_0540
Predicted coding region AF_0540; Hypothetical protein; identified by GeneMark; putative.
       0.773
AF_0541
Predicted coding region AF_0541; Hypothetical protein; identified by GeneMark; putative.
       0.773
pgk
3-phosphoglycerate kinase (pgk); Similar to GB:L77117 SP:Q58058 PID:1592299 percent identity: 48.77; identified by sequence similarity; putative.
  
 
 
 0.762
AF_1420
Membrane protein; Similar to GB:L77117 SP:Q58237 PID:1591514 percent identity: 51.83; identified by sequence similarity; putative.
   
 0.733
AF_2198
Conserved hypothetical protein; Similar to SP:Q10645 PID:1340100 percent identity: 23.28; identified by sequence similarity; putative.
   
 
 0.676
rpl22
LSU ribosomal protein L22P (rpl22P); This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
 
 
 0.671
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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