STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0554Conserved hypothetical protein; Similar to SP:P33014 GB:U00009 PID:405955 GB:U00096 PID:1788322 percent identity: 37.68; identified by sequence similarity; putative; Belongs to the sulfur carrier protein TusA family. (88 aa)    
Predicted Functional Partners:
AF_0553
Thiamine biosynthesis protein (thiF); Similar to SP:P30138 PID:396331 PID:414234 GB:U00096 PID:1790425 percent identity: 38.75; identified by sequence similarity; putative.
 
   
 0.855
AF_0552
Conserved hypothetical protein; Similar to PID:1653220 percent identity: 37.08; identified by sequence similarity; putative; Belongs to the sulfur carrier protein CysO family.
 
 
 
 0.854
iscS1
nifS protein, class-V aminotransferase (nifS-1); Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
   
 
 0.789
iscS2
nifS protein, class-V aminotransferase (nifS-2); Catalyzes the removal of elemental sulfur from cysteine to produce alanine (Probable). Binds 1 2Fe-2S cluster per subunit in a crystal formed under reducing conditions; this subunit provides 1 ligand while IscU provides the other 3 ligands. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
   
 
 0.789
AF_0551
Threonine synthase (thrC-1); Similar to GB:L77117 PID:1592106 percent identity: 40.50; identified by sequence similarity; putative.
       0.786
AF_0555
Predicted coding region AF_0555; Hypothetical protein; identified by GeneMark; putative.
  
  
 0.726
mtaD1
N-ethylammeline chlorohydrolase (trzA-1); Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
  
    0.558
AF_0557
Flavoprotein reductase; Similar to GP:1480407 percent identity: 26.19; identified by sequence similarity; putative.
     
 0.542
AF_1039
Conserved hypothetical protein; Similar to GB:M20144 SP:P40403 PID:289302 GB:AL009126 percent identity: 26.56; identified by sequence similarity; putative.
   
   0.494
AF_0662
Heterodisulfide reductase, subunit A/methylviologen reducing hydrogenase, subunit delta; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
     
 0.490
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.