Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AF_0566Conserved hypothetical protein; Similar to GP:1707787 percent identity: 33.90; identified by sequence similarity; putative. (112 aa)    
Predicted Functional Partners:
AF_0565
nifU protein (nifU-2); Similar to GB:L42023 PID:1003638 PID:1222302 PID:1204625 PID:1573346 percent identity: 55.65; identified by sequence similarity; putative.
       0.790
iscS2
nifS protein, class-V aminotransferase (nifS-2); Catalyzes the removal of elemental sulfur from cysteine to produce alanine (Probable). Binds 1 2Fe-2S cluster per subunit in a crystal formed under reducing conditions; this subunit provides 1 ligand while IscU provides the other 3 ligands. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
       0.788
AF_0563
Conserved hypothetical protein; Similar to GP:1772578 percent identity: 30.77; identified by sequence similarity; putative.
       0.762
nreB
Predicted coding region AF_1590; Involved in DNA damage repair.
 
     0.562
AF_0562
Conserved hypothetical protein; Similar to SP:P39564 PID:2358006 PID:456152 percent identity: 34.29; identified by sequence similarity; putative.
       0.520
rpl30e
LSU ribosomal protein L30E (rpl30E); Similar to GB:L77117 SP:P54061 PID:1591698 percent identity: 41.67; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL30 family.
  
     0.520
rps27e
SSU ribosomal protein S27E (rps27E); Similar to GB:L77117 SP:P54028 PID:1499029 percent identity: 49.02; identified by sequence similarity; putative.
  
     0.502
AF_1308
Thymidylate kinase, putative; Similar to GB:L77117 SP:Q57741 PID:1591015 percent identity: 26.32; identified by sequence similarity; putative.
  
     0.478
AF_2268
Predicted coding region AF_2268; Hypothetical protein; identified by GeneMark; putative.
  
     0.461
rpoL
DNA-directed RNA polymerase, subunit L (rpoL); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
  
     0.456
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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