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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0569DR-beta chain MHC class II; Similar to GP:1223616 percent identity: 37.74; identified by sequence similarity; putative. (60 aa)    
Predicted Functional Partners:
ftsZ2
Cell division protein (ftsZ-2); Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
     
 0.830
AF_0571
Conserved hypothetical protein; Similar to PID:1226043 percent identity: 36.00; identified by sequence similarity; putative.
       0.686
AF_0572
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57900 PID:1499252 percent identity: 34.36; identified by sequence similarity; putative.
       0.577
AF_0573
Predicted coding region AF_0573; Hypothetical protein; identified by GeneMark; putative.
       0.573
AF_0575
Conserved hypothetical protein; Similar to SP:P54501 PID:1303871 GB:AL009126 percent identity: 33.86; identified by sequence similarity; putative.
       0.558
ef1b
Translation elongation factor EF-1, subunit beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
       0.554
AF_0576
Predicted coding region AF_0576; Hypothetical protein; identified by GeneMark; putative.
       0.554
AF_0577
Conserved hypothetical protein; Similar to GB:L77117 PID:1592229 percent identity: 30.20; identified by sequence similarity; putative.
       0.554
cobB2
Transcriptional regulatory protein, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.
   
    0.509
cobB1
Transcriptional regulatory protein, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.
   
    0.509
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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