STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AF_0580Exodeoxyribonuclease III (XthA); Similar to PID:1653682 percent identity: 41.31; identified by sequence similarity; putative (257 aa)    
Predicted Functional Partners:
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
 
 
 0.907
AF_0581
Dolichol-P-glucose synthetase, putative; Similar to GB:L77117 SP:Q58619 PID:1591853 percent identity: 27.50; identified by sequence similarity; putative
       0.852
AF_0582
Hypothetical protein; identified by GeneMark; putative
       0.845
AF_0583
Hypothetical protein; identified by GeneMark; putative
       0.845
AF_0584
Transcriptional regulatory protein, AsnC family; Similar to GB:L77117 SP:Q58133 PID:1591440 percent identity: 35.25; identified by sequence similarity; putative
     
 0.806
AF_0579
Hypothetical protein; identified by GeneMark; putative
     
 0.792
AF_0585
Uncharacterized protein AF_0585; Hypothetical protein; identified by GeneMark; putative
       0.792
AF_0586
Uncharacterized protein AF_0586; Hypothetical protein; identified by GeneMark; putative
       0.792
AF_2430
LacZ expression regulatory protein (Icc); Similar to GB:D16557 SP:P36650 PID:453396 PID:882562 GB:U00096 percent identity: 29.55; identified by sequence similarity; putative
  
  
 0.763
AF_1725
DNA ligase, putative; Similar to SP:P54875 GB:AE000666 PID:1279773 percent identity: 32.69; identified by sequence similarity; putative
  
 0.750
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus DSM4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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