Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AF_0624Conserved hypothetical protein; Similar to GB:L77117 SP:Q58203 PID:1499615 percent identity: 35.82; identified by sequence similarity; putative. (185 aa)    
Predicted Functional Partners:
AF_0462
Conserved hypothetical transmembrane protein; Similar to GB:L77117 SP:Q57882 PID:1591144 percent identity: 33.08; identified by sequence similarity; putative.
 
   
 0.825
dtdA
Conserved hypothetical protein; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
  
    0.782
lig
DNA ligase (lig); DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
       0.773
egsA
Sn-glycerol-1-phosphate dehydrogenase (gldA); Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family.
  
  
 0.729
proS
prolyl-tRNA synthetase (proS); Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
 
     0.626
argS
arginyl-tRNA synthetase (argS); Similar to GB:L77117 SP:Q57689 PID:1590971 percent identity: 48.77; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.624
hmgA
3-hydroxy-3-methylglutaryl-coenzyme A reductase (mvaA); Converts HMG-CoA to mevalonate.
       0.624
AF_0256
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57600 PID:1498904 percent identity: 39.08; identified by sequence similarity; putative.
       0.581
srp54
Signal recognition particle, subunit SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY (Probable). Belongs to the GTP-binding SRP family. SRP54 subfamily.
       0.556
rnhB
Ribonuclease HII (rnhB); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
       0.554
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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