Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
eif5aTranslation initiation factor eIF-5A (eif5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (128 aa)    
Predicted Functional Partners:
rpl21e
LSU ribosomal protein L21E (rpl21E); Similar to GB:L77117 SP:P54013 PID:1590841 percent identity: 53.19; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL21 family.
 
 
 0.992
rps17
SSU ribosomal protein S17P (rps17P); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
  
 
 0.991
rps12
SSU ribosomal protein S12P (rps12P); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
 
 
 0.990
rpl13
LSU ribosomal protein L13P (rpl13P); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.988
rps7
SSU ribosomal protein S7P (rps7P); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
 
 
 0.988
rpl18
LSU ribosomal protein L18P (rpl18P); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
 
 
 0.988
rps6e
SSU ribosomal protein S6E (rps6E); Similar to GB:L77117 SP:P54067 PID:1591894 percent identity: 50.83; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 
 0.987
rpl18e
LSU ribosomal protein L18E (rpl18E); Similar to SP:P12733 GB:M76567 PID:148774 PID:148776 percent identity: 53.85; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eL18 family.
 
 
 0.987
rps4e
SSU ribosomal protein S4E (rps4E); Similar to GB:L77117 SP:P54039 PID:1591170 percent identity: 48.92; identified by sequence similarity; putative; Belongs to the eukaryotic ribosomal protein eS4 family.
  
   0.987
rps2
SSU ribosomal protein S2P (rps2P); Similar to GB:L77117 SP:P54109 PID:1591644 percent identity: 58.33; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS2 family.
 
 
 0.986
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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