Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AF_0649Conserved hypothetical protein; Similar to GB:L77117 PID:1592156 percent identity: 39.55; identified by sequence similarity; putative; Belongs to the UPF0280 family. (233 aa)    
Predicted Functional Partners:
AF_1186
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57564 PID:1498865 percent identity: 56.43; identified by sequence similarity; putative.
 
   
 0.902
AF_1185
Iron-sulfur cluster binding protein; Similar to GB:L77117 SP:Q57563 PID:1590877 percent identity: 36.67; identified by sequence similarity; putative.
 
   
 0.878
AF_0648
Conserved hypothetical protein; Similar to GB:L77117 PID:1591809 percent identity: 29.58; identified by sequence similarity; putative.
  
    0.781
icd
Isocitrate dehydrogenase, NADP (icd); Similar to GB:J02799 SP:P08200 PID:146432 GB:U00096 PID:1651560 percent identity: 57.18; identified by sequence similarity; putative; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
       0.773
AF_1608
Spermidine/putrescine ABC transporter, ATP-binding protein (potA); Similar to GB:M64519 SP:P23858 PID:147326 GB:U00096 PID:1651555 percent identity: 50.16; identified by sequence similarity; putative.
   
    0.556
asd
Aspartate-semialdehyde dehydrogenase (asd); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
       0.522
eif5a
Translation initiation factor eIF-5A (eif5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
       0.490
AF_0646
Agmatinase (speB); Similar to GB:M32363 SP:P16936 PID:147859 PID:551839 PID:882466 percent identity: 33.33; identified by sequence similarity; putative; Belongs to the arginase family.
       0.490
AF_0650
Predicted coding region AF_0650; Hypothetical protein; identified by GeneMark; putative.
       0.487
cysS
cysteinyl-tRNA synthetase (cysS); Similar to GB:D26185 SP:Q06752 GB:L14580 GB:X73989 PID:289284 percent identity: 46.12; identified by sequence similarity; putative.
   
    0.443
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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