Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AF_0651Predicted coding region AF_0651; Hypothetical protein; identified by GeneMark; putative. (76 aa)    
Predicted Functional Partners:
top6B
DNA topoisomerase VI, subunit B (top6B); Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
       0.906
top6A
DNA topoisomerase VI, subunit A (top6A); Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family.
       0.681
srp54
Signal recognition particle, subunit SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY (Probable). Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
    0.629
AF_0650
Predicted coding region AF_0650; Hypothetical protein; identified by GeneMark; putative.
       0.620
hmgA
3-hydroxy-3-methylglutaryl-coenzyme A reductase (mvaA); Converts HMG-CoA to mevalonate.
     
 0.497
AF_0439
Transcriptional regulatory protein, AsnC family; Similar to GB:L77117 SP:Q57615 PID:1498922 percent identity: 29.80; identified by sequence similarity; putative.
   
 
 0.458
AF_0584
Transcriptional regulatory protein, AsnC family; Similar to GB:L77117 SP:Q58133 PID:1591440 percent identity: 35.25; identified by sequence similarity; putative.
   
 
 0.458
AF_1121
Transcriptional regulatory protein, AsnC family; Similar to SP:P42180 percent identity: 35.79; identified by sequence similarity; putative.
   
 
 0.458
AF_1148
Transcriptional regulatory protein, AsnC family; Similar to GB:L77117 SP:Q57615 PID:1498922 percent identity: 32.62; identified by sequence similarity; putative.
   
 
 0.458
AF_1622
Leucine responsive regulatory protein (lrp); Similar to GP:1262197 percent identity: 29.05; identified by sequence similarity; putative.
   
 
 0.458
Your Current Organism:
Archaeoglobus fulgidus
NCBI taxonomy Id: 224325
Other names: A. fulgidus DSM 4304, Archaeoglobus fulgidus DSM 4304, Archaeoglobus fulgidus VC-16, Archaeoglobus fulgidus str. DSM 4304, Archaeoglobus fulgidus strain DSM 4304
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